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Pharm > S3E3: Rheum > Flashcards

S3E3: Rheum Flashcards

1
Q

Hydroxychlorquine

A

Immunomodulator

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2
Q

Sulfasalasine

A

Immunomodulator

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3
Q

Methotrexate

A

Immunosuppressant

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4
Q

leflunomide

A

Immunosuppressant

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5
Q

cyclophosphamide

A

Immunosuppressant

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6
Q

cyclosporine

A

Immunosuppressant

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7
Q

azathioprine

A

Immunosuppressant

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8
Q

mycophenlate

A

Immunosuppressant

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9
Q

Infliximab (remicade)

A

TNF-alpha inhibitor

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10
Q

Entanercept

A

TNF-alpha inhibitor

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11
Q

Adalimumab (humira)

A

TNF-alpha inhibitor

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12
Q

Golimumab

A

TNF-alpha inhibitor

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13
Q

Certolizumab

A

TNF-alpha inhibitor

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14
Q

Abatacept

A

Inhibit T cell activation

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15
Q

Rituximab

A

Inhibit cell cycle initiation

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16
Q

Anakinra

A

IL-1 inhibitor

17
Q

Tocilizumab

A

IL-6 inhibitor

18
Q

Tofacitinib (Xelganz)

A

JAK inhibitor

19
Q

colchicine

A

Interrupts MSU deposition

20
Q

probenecid

A

uricosuric agent

21
Q

isosartan

A

uricosuric agent

22
Q

fenobrate

A

uricosuric agent

23
Q

allopurinol

A

xanthine oxidase inhibitor (lowers uric acid)

24
Q

febuxistat

A

xanthine oxidase inhibitor (lowers uric acid)

25
Q

Gout tx: Prevention

A

low dose colchicine + low dose NSAID

26
Q

Gout tx: Acute (for mild and mod)

A

Mild attack: monotherapy (NSAID or colchicine or steroid)

Mod attack: colchicine + either NSAID or steroid

27
Q

Gout tx: drugs to lower uric acid

A

Allopurinol or fubuxistat

28
Q

RA tx (for mild, mod, and systemic sx)

A

Mild: NSAIDs
Mod: MTX 1st. Then add TNF-alpha inhibitor.
Systemic sx: hydroxychloroquine.

29
Q

DMARDs

A

Immunomodulators
Immunosuppressants
Biologics (TNF-i, -mabs, -JAK, IVIG)

Pharm (37 decks)

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