S1E5: Arrhythmia drugs

Question 1

Disopyramide (Norpace)

Answer 1

Class I, subgroup 1A, Na channel blocker

Question 2

Quinidine (Quinidex)

Answer 2

Class I, subgroup 1A, Na channel blocker

Question 3

Procainamide (Procan)

Answer 3

Class I, subgroup 1A, Na channel blocker

Question 4

Lidocaine (Xylocaine)

Answer 4

Class I, subgroup 1B, Na channel blocker

Question 5

Mexiletine (Mexitil)

Answer 5

Class I, subgroup 1B, Na channel blocker

Question 6

Flecainide (Tambocor)

Answer 6

Class I, subgroup 1C, Na channel blocker

Question 7

Propafenone (Rythmol)

Answer 7

Class I, subgroup 1C, Na channel blocker

Question 8

Metoprolol

Answer 8

Class II, beta blocker

Question 9

esmolol

Answer 9

Class II, beta blocker

Question 10

atenolol

Answer 10

Class II, beta blocker

Question 11

amiodarone *

Answer 11

Class III, K channel blocker, (also has Ib, II, and IV class activity)

Question 12

dronedarone (multaq)*

Answer 12

Class III, K channel blocker, (also has Ib, II, and IV class activity)

Question 13

sotalol (betapace)

Answer 13

Class III, K channel blocker, (also 50% beta blocker activity)

Question 14

Dofetilide (tikosyn)

Answer 14

Class III, K channel blocker

Question 15

Ibutilide (Corvert)

Answer 15

Class III, K channel blocker

Question 16

Verapamil

Answer 16

Class IV, CCB (nondihydropyridine)

Question 17

Diltiazem

Answer 17

Class IV, CCB (nondihydropyridine)

Question 18

Adenosine

Answer 18

Not in class. Works in AV node&raquo_space; SA node

Question 19

Magnesium (tx use)

Answer 19

Tx of digitalis toxicity, torsades de pointes, SVT (in Mg deficiency)

Question 20

Potassium (tx uses)

Answer 20

Used to normalize if hypokalemic (would cause arrhythmia)

Question 21

Tx of A fib

Answer 21

1. Control Rate (CCB, beta blocker, digoxin)
2. Control Rhythm (cardiovert, ibutilide, dofetilidie)
3. Anticoagulate (ASA, warfarin, pradaxa, plavix)

Question 22

Tx of SVT

Answer 22

Control ventricular rate: Adenosine (1st choice), verapamil, dilt, esmolol

Question 23

Tx of VT

Answer 23

Acute: Cardiovert +/- epi, amiodarone

Long term: beta blocker, amiodarone, AICD

Question 24

Tx of Torsades

Answer 24

Correct electrolytes, IV mag, IV isoproterenol (beta agonist)

Question 25

Tx of VF

Answer 25

Acute: Cardiovert +/- epi, amiodarone

Long term: beta blocker, AICD