S1E5: Arrhythmia drugs Flashcards
Disopyramide (Norpace)
Class I, subgroup 1A, Na channel blocker
Quinidine (Quinidex)
Class I, subgroup 1A, Na channel blocker
Procainamide (Procan)
Class I, subgroup 1A, Na channel blocker
Lidocaine (Xylocaine)
Class I, subgroup 1B, Na channel blocker
Mexiletine (Mexitil)
Class I, subgroup 1B, Na channel blocker
Flecainide (Tambocor)
Class I, subgroup 1C, Na channel blocker
Propafenone (Rythmol)
Class I, subgroup 1C, Na channel blocker
Metoprolol
Class II, beta blocker
esmolol
Class II, beta blocker
atenolol
Class II, beta blocker
amiodarone *
Class III, K channel blocker, (also has Ib, II, and IV class activity)
dronedarone (multaq)*
Class III, K channel blocker, (also has Ib, II, and IV class activity)
sotalol (betapace)
Class III, K channel blocker, (also 50% beta blocker activity)
Dofetilide (tikosyn)
Class III, K channel blocker
Ibutilide (Corvert)
Class III, K channel blocker
Verapamil
Class IV, CCB (nondihydropyridine)
Diltiazem
Class IV, CCB (nondihydropyridine)
Adenosine
Not in class. Works in AV node»_space; SA node
Magnesium (tx use)
Tx of digitalis toxicity, torsades de pointes, SVT (in Mg deficiency)
Potassium (tx uses)
Used to normalize if hypokalemic (would cause arrhythmia)
Tx of A fib
- Control Rate (CCB, beta blocker, digoxin)
- Control Rhythm (cardiovert, ibutilide, dofetilidie)
- Anticoagulate (ASA, warfarin, pradaxa, plavix)
Tx of SVT
Control ventricular rate: Adenosine (1st choice), verapamil, dilt, esmolol
Tx of VT
Acute: Cardiovert +/- epi, amiodarone
Long term: beta blocker, amiodarone, AICD
Tx of Torsades
Correct electrolytes, IV mag, IV isoproterenol (beta agonist)
