S2E3: Abx coverage Flashcards
Natural PCN
gram + (staph, strep, syphillis, clostridium)
~gram -
Anti-staph PCN
only MSSA
extended spectrum PCN
amox/amp: gram + (strep pneumo.)
piper/ticar: gram - (pseudomonas)
1st gen cephalosporin
gram + (staph, strep).
~gram - (E. coli, Klebsiella)
2nd gen cephalosporin
less gram + (strep pneumo)
more gram - (H. flu, M. cat)
3rd gen cephalosporin
much less gram + (not staph)
mostly gram - (gonorrhea)
tx: meningitis (crosses BBB)
4th gen cephalosporin
same coverage as 1st and 3rd combined
pseudomonas, MRSA, S. pneumo
5th gen cephalosporin
broadest spec of cephalosporins.
Gram + and - (MRSA).
tx: CAP
Monboctam (aztreonam)
gram - only.
Hosp drug.
Carbapenems
gram + and -.
Hosp drug.
vancomycin
gram + (MRSA).
No gram -.
daptomycin
gram + (MRSA, VRE).
No gram -.
Fosfomycin
gram + and - in urine only.
cycloserine
resistant TB (mycobacterium)
tetracyclines
Broad spec.
Gram + and -.
Anaerobes.
Atypicals (rickettsiae, chlamydia, mycoplasma, spirochetes)