S3E2: Skeletal msk relaxants Flashcards
atracurium
nondepolarizing neuromusclar blocker
shorter acting
cistracurium
nondepolarizing neuromusclar blocker
shorter acting
rocuronium
nondepolarizing neuromusclar blocker
shorter acting
vecuronium
nondepolarizing neuromusclar blocker
shorter acting
pancuronium
nondepolarizing neuromusclar blocker
longer acting
succinylcholine
depolarizing neuromuscular blocker
nondepolarizing neuromusclar blocker
MOA
competitive antagonist to ACh receptor at neuromuscular junction
neostigmine (type and use)
- acetylchoinesterase inhibitor
- reversal of nondepolarizing blocker
depolarizing neuromuscular blocker MOA
-binds and activates nicotinic receptor once, then blocks any other signal (muscle will remain depolarized, unable to repolarize)
Tx of malignant hyperthermia from succinylcholine + volatile anesthetics
dantrolene
dantrolene (dantrium)
spasmolytic
diasepam (valium)
spasmolytic
baclofen (lioresal)
spasmolytic
tizanidine (zanaflex)
spasmolytic
gabapentin (neurontin)
spasmolytic