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Pharm > S2E4: Pregnancy/lactation > Flashcards

S2E4: Pregnancy/lactation Flashcards

1
Q

1 mo before conception

A

400-800 mcg folic acid

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2
Q

3-12 w after conception (whats happening?)

A

organogenesis

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3
Q

Category A

A

Human studies show no risk

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4
Q

Category B

A

Ok in animals, not studied in humans.

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5
Q

Category C

A

Animals show bad effects. Use if benefit > risk

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6
Q

Category D

A

Evidence of human risk. Could still use is benefit > risk

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7
Q

Category X

A

Animal or human studies show fetal risk > benefit

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8
Q

Peri-conception rx

A

folic acid 400 mcg

flu vaccine 2nd or 3rd trimester

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9
Q

Morning sickness tx

A

doxylamine, vit B6 (pyridoxine), meclizine, dimenhydrinate, diphenhydramine, ondasetron, metoclopramide, phenothiazines

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10
Q

Heart burn tx during pregnancy

A

1: antacids (mag, Al, Ca carbonate), sucralfate
2: H2 blocker, PPI

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11
Q

Constipation tx during pregnancy

A
  1. metamucil, citrucel, surfactants
  2. stimulants
    * avoid mineral oil
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12
Q

HA tx during pregnancy

A

rest, ice, APAP

*avoid NSAIDs, migraine rx (triptans, ergotamine)

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13
Q

Coag d/o tx during pregnancy

A

heparin (unfrac or frac OK)
enoxaparin (LMWH)
*NO WARFARIN after 6 wk

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14
Q

GDM tx

A
  1. insulin (NPH/intermediate + regular insulin)

2. metformin (glyburide)

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15
Q

HTN (pregnancy induced) tx

A
  1. Methyldopa + Ca
  2. Labetolol, nifedipine
    * NO ACE-I or ARB
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16
Q

UTI tx during pregnancy

A

Ampicillin, cephalexin, nitrofurantoin

*No tetracyclines or FQL

17
Q

Syphilis tx during pregnancy

A

PCN

18
Q

Gonorrhea tx during pregnancy

A

ceftriaxone

19
Q

Chlamydia tx during pregnancy

A

erythromycin

20
Q

asthma tx during pregnancy

A

albuterol and inhaled corticosteroids (flovent)

21
Q

Allergic rhinitis tx during pregnancy

A

inhaled corticosteroids and 1st gen antihistamines (diphenhydramine)
2nd gen antihystamine (Cetirazine (zyrtec) and Loratadine (claritin)) only if clearly needed.

22
Q

Depression tx during pregnancy

A
  1. SSRIs (fluoxetine, sertraline, citalopram) with TCAs (amitryptyline, nortriptyline)
  2. buproprion
    * No paroxetine (SSRI) during pregnancy, but preferred during lactation
23
Q

Depression tx during lactation

A
  1. sertraline, paroxetine, or TCAs

* avoid fluoxetine (transition to paroxetine or sertraline after delivery)

24
Q

Allergic rhinitis tx during lactation

A

short term: antihistamines

long term: nasal steroid or cromlyn

25
Q

asthma tx during lactation

A

inhaled steroids (flovent)

26
Q

HTN tx during lactation

A

labetalol, atenolol, metoprolol, nifedipine, enalapril, captopril

  • labetalol, nifedipine also ok in pregnancy
  • enalapril, captopril only ACE-Is that are ok (but remember, not in pregnancy!!)
  • no ARBs

Pharm (37 decks)

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