S2E3: Abx

Question 1

Beta lactam abx (classes)

Answer 1

penicillins, cephalosporins, carbapenems, monobactam abx.

Bactericidal.

Question 2

Penicillin G

Answer 2

Natural penicillin. IV/IM.

Question 3

Penicillin V

Answer 3

Natural penicillin. PO.

Question 4

Cloxacillin

Answer 4

Anti-staph penicillin (penicillinase resistant)

Question 5

Nafcillin

Answer 5

Anti-staph penicillin (penicillinase resistant)

Question 6

Oxacillin

Answer 6

Anti-staph penicillin (penicillinase resistant)

Question 7

Ampicillin

Answer 7

Extended spectrum penicillin (anti-strep pneumo)

Question 8

Amoxicillin

Answer 8

Extended spectrum penicillin (anti-strep pneumo)

Question 9

Piperacillin

Answer 9

Extended spectrum penicillin (antipseudomonal)

Question 10

Ticarcillin

Answer 10

Extended spectrum penicillin (antipseudomonal)

Question 11

beta-lactamase inhibitor

Answer 11

Used in combination with penicillin (increases spectrum)

Question 12

Augmentin (amoxicillin + clavulanic acid)

Answer 12

penicillin + beta-lactamase inhibitor

Question 13

Unasyn (ampicillin + sulbactam)

Answer 13

penicillin + beta-lactamase inhibitor

Question 14

Timentin (ticarcillin + clavulanic acid)

Answer 14

penicillin + beta-lactamase inhibitor

Question 15

Zosyn (piperacillin + tazobactam)

Answer 15

penicillin + beta-lactamase inhibitor

Question 16

cefaxdroxil (duricef)

Answer 16

1st gen cephalosporin

Question 17

cefazolin (ancef)

Answer 17

1st gen cephalosporin

Question 18

cephalexin (keflex)

Answer 18

1st gen cephalosporin

Question 19

cefuroxime (ceftin, zincef)

Answer 19

2nd gen cephalosporin

Question 20

cefprozil (cefzil)

Answer 20

2nd gen cephalosporin

Question 21

cefixime (suprax)

Answer 21

3rd gen cephalosporin

Question 22

ceftazidime

Answer 22

3rd gen cephalosporin

Question 23

ceftriaxone (rocephin)

Answer 23

3rd gen cephalosporin

Question 24

cefdinir (omnicef)

Answer 24

3rd gen cephalosporin

Question 25

cefepime (maxipime)

Answer 25

4th gen cephalosporin

Question 26

ceftaroline (teflarco)

Answer 26

5th gen cephalosporin

Question 27

aztreonam

Answer 27

monobactam

Question 28

imipenem

Answer 28

carbapenem

Question 29

ertapenem

Answer 29

carbapenem

Question 30

meropenem

Answer 30

carbapenem

Question 31

doripenem

Answer 31

carbapenem

Question 32

Cell wall abx (non-lactams)

Answer 32

vancomycin, daptomycin, fosfomycin, cycloserine.

Question 33

Vancomycin

Answer 33

cell wall abx. bactericidal (slow)

Question 34

daptomycin

Answer 34

cell wall abx. bactericidal.

Question 35

fosfomycin

Answer 35

cell wall abx. bactericidal (urine only)

Question 36

cycloserine

Answer 36

cell wall abx. bacteriostatic at [low]; bactericidal at [high]

Question 37

Protein synthesis inhibitors (inhibits ribosomes)

Answer 37

bacteriostatic: tetracycline, macrolides, clindamycin, oxazolidones. bactericidal: aminoglycosides.

Question 38

doxycycline (vibramycin)

Answer 38

tetracyclines

Question 39

demecloclycline (declomycin)

Answer 39

tetracyclines

Question 40

minocycline (minocin)

Answer 40

tetracyclines

Question 41

oxytetracycline (terramycin)

Answer 41

tetracyclines

Question 42

tigecycline (tygacil)

Answer 42

tetracyclines

Question 43

erythromycin

Answer 43

macrolide

Question 44

clarithromycin (biaxin)

Answer 44

macrolide

Question 45

azithromycin (zithromax)

Answer 45

macrolide

Question 46

fidaxomicin (dificid)

Answer 46

macrolide

Question 47

telithromycin (keteck)

Answer 47

macrolide

Question 48

clindamycin

Answer 48

inhibits bacterial ribosomes

Question 49

linezolid (zyvox)

Answer 49

oxazolidinones

Question 50

neomycin

Answer 50

aminoglycoside

Question 51

streptomycin

Answer 51

aminoglycoside

Question 52

amikacin

Answer 52

aminoglycoside

Question 53

gentamicin

Answer 53

aminoglycoside

Question 54

tobramycin

Answer 54

aminoglycoside

Question 55

kanamycin

Answer 55

aminoglycoside

Question 56

metronidazole (flagyl)

Answer 56

disrupts DNA helix. Bactericidal.

Question 57

Folic acid synthesis inhibitors

Answer 57

Sulfonamides, TMP. Bacteriostatic.

Question 58

sodium sulfacetamide (Bleph 10)

Answer 58

topical sulfonamide

Question 59

silver sulfadiazine (silvadene)

Answer 59

topical sulfonamide

Question 60

sulfasalazine (azulfidine)

Answer 60

oral sulfonamide

Question 61

sulfadiazine

Answer 61

oral sulfonamide

Question 62

sulfamethoxazole

Answer 62

oral sulfonamide

Question 63

sulfisoxazole

Answer 63

oral sulfonamide

Question 64

TMP/SMP (bactrim)

Answer 64

TMP (folic acid synthesis inhibitor- step 2) + sulfa drug (folic acid synthesis inhibitor- step 1)

Question 65

Fluoroquinolones

Answer 65

inhibit topoisomerase. bactericidal.

Question 66

ciprofloxacin (cipro)

Answer 66

fluoroquinolones

Question 67

gemifloxacin (factive)

Answer 67

resp fluoroquinolones

Question 68

levofloxacin (levaquin)

Answer 68

resp fluoroquinolones

Question 69

moxifloxacin (avelox)

Answer 69

resp fluoroquinolones

Question 70

norfloxacin (noroxin)

Answer 70

fluoroquinolones (for UTI only)

Question 71

ofloxacin (floxin)

Answer 71

fluoroquinolones

Question 72

gatifloxacin

Answer 72

fluoroquinolones

Question 73

nitrofurantoin (macrobid)

Answer 73

inhibits acetyl CoA. bacteriostatic.

Question 74

Antimycobacterial drugs

Answer 74

isoniazid (INH), Rifampin, Ethambutol, Pyrazinamide, streptomycin. *streptomycin is aminoglycoside