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Pharm > S2E3: Abx > Flashcards

S2E3: Abx Flashcards

1
Q

Beta lactam abx (classes)

A

penicillins, cephalosporins, carbapenems, monobactam abx.

Bactericidal.

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2
Q

Penicillin G

A

Natural penicillin. IV/IM.

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3
Q

Penicillin V

A

Natural penicillin. PO.

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4
Q

Cloxacillin

A

Anti-staph penicillin (penicillinase resistant)

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5
Q

Nafcillin

A

Anti-staph penicillin (penicillinase resistant)

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6
Q

Oxacillin

A

Anti-staph penicillin (penicillinase resistant)

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7
Q

Ampicillin

A

Extended spectrum penicillin (anti-strep pneumo)

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8
Q

Amoxicillin

A

Extended spectrum penicillin (anti-strep pneumo)

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9
Q

Piperacillin

A

Extended spectrum penicillin (antipseudomonal)

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10
Q

Ticarcillin

A

Extended spectrum penicillin (antipseudomonal)

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11
Q

beta-lactamase inhibitor

A

Used in combination with penicillin (increases spectrum)

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12
Q

Augmentin (amoxicillin + clavulanic acid)

A

penicillin + beta-lactamase inhibitor

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13
Q

Unasyn (ampicillin + sulbactam)

A

penicillin + beta-lactamase inhibitor

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14
Q

Timentin (ticarcillin + clavulanic acid)

A

penicillin + beta-lactamase inhibitor

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15
Q

Zosyn (piperacillin + tazobactam)

A

penicillin + beta-lactamase inhibitor

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16
Q

cefaxdroxil (duricef)

A

1st gen cephalosporin

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17
Q

cefazolin (ancef)

A

1st gen cephalosporin

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18
Q

cephalexin (keflex)

A

1st gen cephalosporin

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19
Q

cefuroxime (ceftin, zincef)

A

2nd gen cephalosporin

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20
Q

cefprozil (cefzil)

A

2nd gen cephalosporin

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21
Q

cefixime (suprax)

A

3rd gen cephalosporin

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22
Q

ceftazidime

A

3rd gen cephalosporin

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23
Q

ceftriaxone (rocephin)

A

3rd gen cephalosporin

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24
Q

cefdinir (omnicef)

A

3rd gen cephalosporin

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25
Q

cefepime (maxipime)

A

4th gen cephalosporin

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26
Q

ceftaroline (teflarco)

A

5th gen cephalosporin

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27
Q

aztreonam

A

monobactam

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28
Q

imipenem

A

carbapenem

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29
Q

ertapenem

A

carbapenem

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30
Q

meropenem

A

carbapenem

31
Q

doripenem

A

carbapenem

32
Q

Cell wall abx (non-lactams)

A

vancomycin, daptomycin, fosfomycin, cycloserine.

33
Q

Vancomycin

A

cell wall abx. bactericidal (slow)

34
Q

daptomycin

A

cell wall abx. bactericidal.

35
Q

fosfomycin

A

cell wall abx. bactericidal (urine only)

36
Q

cycloserine

A

cell wall abx. bacteriostatic at [low]; bactericidal at [high]

37
Q

Protein synthesis inhibitors (inhibits ribosomes)

A

bacteriostatic: tetracycline, macrolides, clindamycin, oxazolidones.
bactericidal: aminoglycosides.

38
Q

doxycycline (vibramycin)

A

tetracyclines

39
Q

demecloclycline (declomycin)

A

tetracyclines

40
Q

minocycline (minocin)

A

tetracyclines

41
Q

oxytetracycline (terramycin)

A

tetracyclines

42
Q

tigecycline (tygacil)

A

tetracyclines

43
Q

erythromycin

44
Q

clarithromycin (biaxin)

45
Q

azithromycin (zithromax)

46
Q

fidaxomicin (dificid)

47
Q

telithromycin (keteck)

48
Q

clindamycin

A

inhibits bacterial ribosomes

49
Q

linezolid (zyvox)

A

oxazolidinones

50
Q

neomycin

A

aminoglycoside

51
Q

streptomycin

A

aminoglycoside

52
Q

amikacin

A

aminoglycoside

53
Q

gentamicin

A

aminoglycoside

54
Q

tobramycin

A

aminoglycoside

55
Q

kanamycin

A

aminoglycoside

56
Q

metronidazole (flagyl)

A

disrupts DNA helix. Bactericidal.

57
Q

Folic acid synthesis inhibitors

A

Sulfonamides, TMP. Bacteriostatic.

58
Q

sodium sulfacetamide (Bleph 10)

A

topical sulfonamide

59
Q

silver sulfadiazine (silvadene)

A

topical sulfonamide

60
Q

sulfasalazine (azulfidine)

A

oral sulfonamide

61
Q

sulfadiazine

A

oral sulfonamide

62
Q

sulfamethoxazole

A

oral sulfonamide

63
Q

sulfisoxazole

A

oral sulfonamide

64
Q

TMP/SMP (bactrim)

A

TMP (folic acid synthesis inhibitor- step 2) + sulfa drug (folic acid synthesis inhibitor- step 1)

65
Q

Fluoroquinolones

A

inhibit topoisomerase. bactericidal.

66
Q

ciprofloxacin (cipro)

A

fluoroquinolones

67
Q

gemifloxacin (factive)

A

resp fluoroquinolones

68
Q

levofloxacin (levaquin)

A

resp fluoroquinolones

69
Q

moxifloxacin (avelox)

A

resp fluoroquinolones

70
Q

norfloxacin (noroxin)

A

fluoroquinolones (for UTI only)

71
Q

ofloxacin (floxin)

A

fluoroquinolones

72
Q

gatifloxacin

A

fluoroquinolones

73
Q

nitrofurantoin (macrobid)

A

inhibits acetyl CoA. bacteriostatic.

74
Q

Antimycobacterial drugs

A

isoniazid (INH), Rifampin, Ethambutol, Pyrazinamide, streptomycin.
*streptomycin is aminoglycoside

Pharm (37 decks)

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