Rubin's 9: Infectious & Parasitic Diseases

Question 1

The circulating atypical lymphocytes seen in smears with patients with EBV are:

Answer 1

Activated T cells

Question 2

Responsible organism: Erythema chronicum migrans, then migratory musculoskeletal pain, then cardiac or neurologic abnormalities like meningitis or facial nerve palsy.

Answer 2

Borrelia burgdorferi - spirochete; Lyme disease

Question 3

What bug is associated with meningitis and Waterhouse-Friderichsen syndrome?

Answer 3

Neisseria meningitidis

Question 4

Dx: Bird to human transmission; Interstitial pneumonia; Persisten dry cough, fever, HA etc.

Answer 4

Psittacosis - pneumonia; Chlamydia psittaci

Question 5

Dx: Giant cell pneumonia with “Warthin-Finkeldey giant cells”

Answer 5

Measles pneumonia

Question 6

What kind of granulomas are found in TB?

Answer 6

Caseating - soft core surrounded by epithelioid macrophages, Laghans giant cells, lymphocytes, peripheral fibrosis

Question 7

Dx: Rash, arthralgias, transient defect in erythropoiesis; Virus; Spread by respiratory secretions; Erythema infectiosum

Answer 7

Parvovirus B19 - DNA virus Can cause aplastic crisis in people with hemolytic anemia/SCD.