Pathoma 10.4 Stomach Flashcards

1
Q

Dx: Congenital malformation of the abdominal wall, leads to exposure of abdominal contents

A

Gastroschisis

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2
Q

Dx: Persistent herniation of the bowel into the umbilical cord; Failure of herniated intestines to return to the body cavity during development;

A

Omphalocele Covered by peritoneum and amnion (how you can tell the difference between omphalocele and gastroschisis)

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3
Q

Dx: Congenital hypertrophy of pyloric smooth muscle; Projectile vomiting; Visible peristalsis; Olive-like mass in abdomen More common in males

A

Pyloric stenosis

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4
Q

What is the treatment for pyloric stenosis?

A

Myotomy

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5
Q

Dx: Acidic damage to mucosa due to imbalances between mucosal defenses and acidic environment

A

Acute gastritis

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6
Q

A Cushing ulcer (increased intracranial pressure) is a risk factor for:

A

Acute gastritis Cushing ulcer (increased intracranial pressure) –> increased vagal stimulation

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7
Q

Chronic gastritis is what type of hypersensitivity reaction?

A

Type 4 T-cell mediated damage antibodies against parietal cells or intrinsic factor

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8
Q

Chronic gastritis involved what parts of the stomach?

A

Body and fundus if autoimmune (antrum if H. pylori) Knocking out parietal cells –> knocking out the ability to produce acid

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9
Q

Chronic gastritis is the most common cause of:

A

Pernicious anemia (B12 deficiency)

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10
Q

Patients with autoimmune chronic gastritis are at increased risk for

A

Gastric adenocarcinoma (from intestinal metaplasia)

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11
Q

Patients with H. Pylori chronic gastritis are at increased risk for what 3 things?

A
  1. ulceration 2. gastric adenocarcinoma 3. MALT lymphoma
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12
Q

ZE syndrome causes:

A

Duodenal ulcers

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13
Q

Dx: Epigastric pain that worsens with meals

A

Gastric ulcer usually located on the lesser curvature of the antrum

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14
Q

T/F: Duodenal ulcers are almost never malignant.

A

True

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15
Q

What makes a gastric ulcer benign?

A

Small; punched out appearance; No heaping of mucosa around it or inflammation

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16
Q

What makes a gastric ulcer malignant?

A

Piling up of mucosa around the ulcer; large; irregular border

17
Q

Nitrosamines, present in smoked foods, help explain the increased incidence of:

A

Gastric cancer (in Japan)

18
Q

Dx: Signet ring cells infiltrate gastric wall; Linitis plastica; Not associated with H. Pylori, intestinal metaplasia or nitrosamines

A

Diffuse type of gastric cancer NO ulcers, instead diffusely thickened wall of stomach

19
Q

Where does gastric cancer commonly spread?

A

Left supraclavicular node (Virchow node)

20
Q

What is a Sister Mary Joseph nodule?

A

Distant metastasis of intestinal type of gastric carcinoma at the periumbilical region

21
Q

A Krukenberg tumor is commonly seen with what cancer?

A

Diffuse type of gastric carcinoma distant metastases are bilateral ovaries