RSV Flashcards
1
Q
What does RSV stand for?
A
Respiratory Syncytial Virus
2
Q
RSV is responsible for the most common what in infants and young children?
A
Fatal acute respiratory tract infections
3
Q
Host of RSV
A
Only humans
4
Q
Genome of RSV
A
- negative
- single stranded
- RNA
5
Q
Capsid of RSV
A
Helical
6
Q
Distinguishable clinical presentation of RSV
A
Infants/Young : Lower respiratory tract infections and bronchiolitis
Older: Upper respiratory tract infections and flu like symptoms
7
Q
Other symptoms associated with RSV
A
-flu like symptoms
8
Q
Does RSV cause viremia
A
No
9
Q
Transmission of RSV
A
Aerosols and direct contact
10
Q
What is Bronchiolitis
A
- virus induced necrosis of the bronchiolar epithelium
- hypersecretion of mucus
- inflammatory cell infiltration
- edema
11
Q
Pathology of RSV
A
-multinucleated giant cells
12
Q
Diagnosis of RSV
A
- fluorescent antibody
- antigen detection
- PCR detection of RNA
13
Q
Treatment of RSV
A
- Ribavirin; causes replication/transcription errors and is a G analogue. Also used for flavi, paramxo, bunya, arena, retro, herpes, adeno, pox
14
Q
Treatment of RSV that is not an analogue
A
Palivizumab; a monoclonal antibody which provides passive immunization.
