Parainfluenza Virus Flashcards
1
Q
Which family does Parainfluenza virus belong to
A
Paramyxoviridae
2
Q
Genome of Parainfluenza
A
- negative
- single stranded
- RNA
3
Q
Capsid shape
A
Helical
4
Q
Is it enveloped
A
Yes
5
Q
Attaches by what protein
A
Hemagglutinin and Neuraminidase
6
Q
What protein allows for fusion similar to other Paramyxo.
A
F protein
7
Q
Clinical presentation of Parainfluenza
A
- Upper and lower respiratory tract
- cold symptoms
- pneumonia
- bronchiolitis
8
Q
Distinguishable symptom of Parainfluenza
A
Croup or a barky cough and harsh noisy breathing
9
Q
Pathogenesis of Parainfluenza
A
- damage in the ciliated cells and stay in the in the URT and potentially move from there.
10
Q
HPIV and the response by the immune system
A
- Interferon, interleuken, TNF
- histamine release resulting in croup
11
Q
Transmission of HPIV
A
- close contact with infected persons or objects
- inhalation of droplets
12
Q
Control for HPIV
A
None, just support
