Rhinoviridae Flashcards
1
Q
To what genus does Rhinovirus belong to
A
Piconavirus
2
Q
Rhinovirus is in the same classification as
A
- Enterovirus
2. Hepatitis A
3
Q
Infection of rhinovirus leads to what after interacting with immune system
A
Lifelong immunity
4
Q
Genome of Rhinovirus
A
- positive
- single stranded
- RNA
5
Q
Capsid structure
A
Icosahedral
6
Q
Is it enveloped
A
Rhinovirus is NOT enveloped
7
Q
Location where Rhinovirus takes place
A
Cytoplasm
8
Q
Replication process of Rhinovirus
A
- Viral RNA translated into polyprotein
2. polyprotein cleaved into enzymatic and structural proteins
9
Q
Clinical presentation of Rhinovirus
A
- primarily UR infection, less common LR infection
- common cold
- rare fever
10
Q
Process of rhinovirus
A
- virus enters UR tract
- moves to back of the throat
- virus attaches to cell surface receptors
Infection remains localized in UR tract
11
Q
Process that hurt function of rhinovirus
A
- temperatures above 33C
- stomach acid
12
Q
Incubation period of rhinovirus
A
8-10 hrs
13
Q
Immune response to rhinovirus
A
- interferon gamma
- interleukin 8
- both stimulate cytokine cascade, amplifying immune response
14
Q
Control
A
- none
- symptom management
15
Q
Further complications of rhinovirus
A
- acute otitis media
- asthma exacerbations, sinusitis, chronic bronchitis
