Colorado Tick Fever Virus

Question 1

Virus within the Reoviridae family in the notes

Answer 1

Colorado Tick Fever virus

Question 2

Genus that Colorado tick fever virus is in

Answer 2

Coltivirus

Question 3

Physical characteristic of Colorado tick fever virus

Answer 3

• non enveloped

- icosahedral inner capsid

Question 4

Nucleic acid of colorado tick fever virus

Answer 4

12 ds +of RNA segments

Question 5

Replication of the colorado tick fever virus

Answer 5

Review slide, but since + strand of RNA can act as a “mRNA”

Question 6

Individuals most exposed to colorado tick fever virus, and initial symptom

Answer 6

males aged 15-45, and Febrile illness

Question 7

Symptoms of colorado tick fever virus

Answer 7

• fever with sudden onset; “saddleback” fever
• flulike symptoms; headaches, myalgias, arthralgias, fatigue
• nonspecific transient rash

Question 8

Series complication of colorado tick fever virus

Answer 8

Encephalitis, pericarditis, thrombocytopenia(low platelet count)

Question 9

Cells colorado tick fever virus infects

Answer 9

Bone marrow cells; arresting development of blood cell types

-leukocytes, eosinophils, basophils

Question 10

Days till onset of symptoms; host cells that contain virus

Answer 10

• symptoms begin 4-5 days up to 20 following tick bite

- circulates inside erythropoietic cells

Question 11

Virus and the life within a red blood cell

Answer 11

• can survive up till 120 days

- antibodies present after 2 weeks.

Question 12

Transmission of colorado tick fever virus and reserve

Answer 12

• wood ticks

- small mammals as reservoir

Question 13

location of colorado tick fever virus

Answer 13

western united states

Question 14

Control of colorado tick fever virus

Answer 14

none; just control of vector and reservoir; limit exposure to ticks