Rheumatology Flashcards

1
Q

Sacroiliitis
Bamboo spine
Gets better with activity
+HLA B27
Associated with IBD, uveitis, aortitis

A

Ankylosing spondylitis

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2
Q

Malar rash or heliotropic
< 10 yo
Proximal Muscle weakness
Scaly skin (gottrons sign)
Periungual red bumps (telangiectasias)
Elevated CK

A

Juvenile dermatomyositis

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3
Q

Labs to order for diagnosis of juvenile dermatomyositis

A

CPK
LDH
aldolase

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4
Q

Most common systemic vasculitis in children

A

Henoch schonlein purpura

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5
Q

Palpable purpura
Abdominal pain
Hematuria, proteinuria, azometemia, HTN

A

Henoch schonlein purpura

(IgA vasculitis)

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6
Q

Most common rheumatologic disease in childhood

A

Juvenile idiopathic arthritis

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7
Q

Morning stiffness
Arthritis
<16 yo
+ANA
Uveitis (oligoarticular)

A

Juvenile idiopathic arthritis

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8
Q

Complications of juvenile idiopathic arthritis

A

High fevers
Leukocytosis
Rash - salmon colored with central clearings which coalesce and are evanescent
HSM
LAD
Pleuritis, pericarditis, serositis

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9
Q

1 treatable cause of blindness in children.

A

Chronic uveitis

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10
Q

Treatment for juvenile idiopathic arthritis

A

PT/OT
#1 NSAIDs
#2 steroids + immunosuppressants
Methotrexate (gold standard)

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11
Q

Main side effects of methotrexate

A

Folate antagonist
GI distress
Pulmonary toxicity

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12
Q

Criteria for Kawasaki disease

A

Fever > 5 days
Cervical LAD
Oropharyngeal findings
Bilateral conjunctivitis (not Exudative)
Diffuse rash
Erythema/edema of hands/feet

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13
Q

Sterile pyuria
CNS symptoms
Migratory Polyarthritis
Hydrops in gallbladder
Thrombocytosis

A

Minor symptoms of Kawasaki disease

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14
Q

Complication of Kawasaki disease

A

Coronary artery aneurysm/vasculitis

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15
Q

Treatment for Kawasaki disease

A

IVIG - 2g/kg
Aspirin 80mg/kg/day following by maintenance therapy if 5mg/kg/day

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16
Q

Duration to avoid measles and varicella vaccines after IVIG

A

11 mo

17
Q

Erythema chonicum migrans

A

Lyme disease

Borrelia burgdorferi
Ixodes deer tick

18
Q

Best way to prevent Lyme disease

A

Frequent tick checks

19
Q

First 2 week symptoms of Lyme disease

A

Erythema chronicum migrans
Arthralgia
Fatigue

20
Q

Several month symptoms of Lyme disease

A

CNS (Bells palsy)
Cardiac
Arthritis

21
Q

Diagnosis and treatment for Lyme disease

A

Lyme EIA or FA
Western blot (confirmatory)

Doxycycline if > 8 yo
Amoxicillin if < 8 yo

22
Q

Treated for Lyme disease
Fevers. Chillls
Sepsis

A

Jarisch-herxheimer reaction

(Release of endotoxin)

23
Q

Arthritis
Uveitis
Urethritis
+ HLA B27
GI or GU infection

A

Reactive arthritis

24
Q

Most common cause of reactive arteries in the US

A

Chlamydia trachomatis

25
Q

Weight loss. Fatigue
Hilar adenopathy. Bilateral peribronchial cuffing
Chronic cough
African Americans
Noncasesting granuloma

A

Sarcoidosis

Arthritis
Rash
Uveitis

26
Q

Complications of sarcoidosis

A

Hypercalcemia
Hypercalciuria
Cardiac

27
Q

Linear hypopigmented patch
Brown border

A

Localized linear scleroderma

28
Q

Treatment for localized linear scleroderma

A

Topical lubricants
Photochemotherapy

Steroids
Anti malaria ms
Immunosuppressant

29
Q

Sclerodactyly
Pulmonary fibrosis
Reflux/dysphagia
Raynaud
Renal crisis syndrome
+ANA
+Anti topoisomerase
+Anti RNA polymerase

A

Systemic scleroderma

30
Q

Diagnostic criteria for SLE

A

Malar or discoid rags
Photosensitivity
Oral ulcerations
Arthritis and serositis
Hematologic abnormalities
Renal abnormalities
CNS/psych abnormalities
+ Anti dsDNA, anti-Smith
+ ANA

31
Q

Rash
3rd degree heart block
Hydrops fetalis
+Anti SSA

A

Neonatal lupus

32
Q

Periodic fever
Aphthous stomatitis
Pharyngitis
Cervical adenitis

Treatment

A

PFAPA syndrome

Prednisone

33
Q

Fever
Abdominal pain
Testicular pain
Knee/ankle swelling

A

Familial Mediterranean fever