Rheumatology Flashcards
Sacroiliitis
Bamboo spine
Gets better with activity
+HLA B27
Associated with IBD, uveitis, aortitis
Ankylosing spondylitis
Malar rash or heliotropic
< 10 yo
Proximal Muscle weakness
Scaly skin (gottrons sign)
Periungual red bumps (telangiectasias)
Elevated CK
Juvenile dermatomyositis
Labs to order for diagnosis of juvenile dermatomyositis
CPK
LDH
aldolase
Most common systemic vasculitis in children
Henoch schonlein purpura
Palpable purpura
Abdominal pain
Hematuria, proteinuria, azometemia, HTN
Henoch schonlein purpura
(IgA vasculitis)
Most common rheumatologic disease in childhood
Juvenile idiopathic arthritis
Morning stiffness
Arthritis
<16 yo
+ANA
Uveitis (oligoarticular)
Juvenile idiopathic arthritis
Complications of juvenile idiopathic arthritis
High fevers
Leukocytosis
Rash - salmon colored with central clearings which coalesce and are evanescent
HSM
LAD
Pleuritis, pericarditis, serositis
1 treatable cause of blindness in children.
Chronic uveitis
Treatment for juvenile idiopathic arthritis
PT/OT
#1 NSAIDs
#2 steroids + immunosuppressants
Methotrexate (gold standard)
Main side effects of methotrexate
Folate antagonist
GI distress
Pulmonary toxicity
Criteria for Kawasaki disease
Fever > 5 days
Cervical LAD
Oropharyngeal findings
Bilateral conjunctivitis (not Exudative)
Diffuse rash
Erythema/edema of hands/feet
Sterile pyuria
CNS symptoms
Migratory Polyarthritis
Hydrops in gallbladder
Thrombocytosis
Minor symptoms of Kawasaki disease
Complication of Kawasaki disease
Coronary artery aneurysm/vasculitis
Treatment for Kawasaki disease
IVIG - 2g/kg
Aspirin 80mg/kg/day following by maintenance therapy if 5mg/kg/day