Nephrology Flashcards
Next step for microscopic hematuria
Repeat UA in few weeks
Next step for persistent microscopic hematuria
Urine Ca/Cr ratio
If elevated, check 24hr total Ca excretion
If > 4 mg/kg/day — confirmed hypercalciuria
Red/pink discoloration in diaper
Urate crystals
Not hematuria
Myoglobinuria
Rhabdomyolysis
Differential for gross hematuria (+ microscopy and red)
HSP and Hereditary nephritis
Benign familial hematuria
MPGN
Alport and IgA nephropathy
Trauma
UPJ obstruction
Renal stones and crystals
Infectious
Abnormal cells
Most common renal stone in children
Calcium
Most sensitive modality to confirm renal stone
Non contrast CT
Predisposing factors of renal stones in IBD
Hyperoxaluria
Hypocitraturia
Best way to decrease urinary calcium excretion and prevent stone formation in urine
Thiazide diuretic
Mechanism of added calcium for renal stones
Decrease absorption of oxalate
Renal stone
Distal RTA 1
Ca phosphate
Orthostatic proteinuria
Proteinuria present during day but disappears when lying down
Best test for orthostatic proteinuria
First void spot urine
If protein disappears when lying down, check sCr. If sCr normal, f/u 3 mo
If protein does not disappear, check Ur p/c ratio. > 0.2 means renal disease
Renal failure
Persistent microscopic hematuria
Sensorineural hearing loss
Ocular defects
X-linked
Alport syndrome (familial nephritis)
Most commonly palpated masses in infants
Hydronephrotic kidneys (from UPJ obstruction)
Multicystic dysplastic kidneys