Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Laughing Your Way > Allergy + Immunology > Flashcards

Allergy + Immunology Flashcards

1
Q

Asthma symptoms occur less than twice per week

Management

A

Intermittent asthma

SABA prn

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Asthma symptoms occur more than twice per week

Management

A

Mild persistent asthma

ICS + SABA prn

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Daily asthma symptoms

A

Moderate persistent asthma

ICS + LABA + SABA prn

(Ie ICS + formeterol)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Asthma symptoms occurring multiple times per day

A

Severe persistent asthma

High dose ICS + LABA + leukotriene receptor antagonist + SABA prn

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Signs of poor asthma control

A

Symptoms > 2x per week
Waking up > 2x per month
Albuterol >2x per week
Steroids >2x per year

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Nasal polyps
Aspirin intolerance
Asthma

A

Aspirin-exacerbated respiratory disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Allergic rhinitis
Tingling sensation in or around mouth when eating a specific food

A

Oral allergy syndrome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Food allergens outgrown by 5 years of age

A

Milk
Egg
Soy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Diagnosis anaphylaxis

Management

A

Involvement of more than one organ system: Derm, Respiratory, CV, GI

1) Airway
2) Epinephrine - 0.01 mg/kg (1:1000)
— 0.3mg if > 30kg
— 0.15mg if < 30kg

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Disorder of phagocytic function
Deep abscess
Pneumonia
Lymphadenitis
Osteomyelitis
Staph aureus, Burkholderia, Serratia, fungi
Aspergillus

A

Chronic Granulomatous Disease (CGD)

NADPH oxidase defect

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Diagnostic test for CGD and management

A

Nitroblue tetrazolium (NBT) test
(assays phagocytic oxidase acitivity)

Ppx: Bactrim and intraconazole

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Defect in chemotaxis
High WBC
Abscess, omphalitis, delayed wound healing
Delayed umbilical separation
No pus

A

Leukocyte Adhesion Deficiency (LAD)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Diagnostic test for LAD and management

A

Flow cytometry

BMT and HSCT

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Abnormal LYST (gene)
Giant inclusion bodies
Abnormal chemotaxis
Frequent infections (skin, lungs)
Easy bruisability
Oculicutaneos albinism
S aureus, S pyogenes, pneumococcus

A

Chediak-Higashi syndrome (CHS)

Autosomal recessive

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

diagnostic test for chediak-Higashi and management

A

Blood smear - giant granules in neutrophils

BMT

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Most common primary immunodeficiency
Recurrent sinopulmonary infections
Not an indication for IVIG replacement

A

IgA deficiency

17
Q

X-linked
Absent B cells
Encapsulated pyogenic bacteria

Management

A

Bruton’s x-linked agammaglobulinemia

IVIG

18
Q

Complications of Bruton agammaglobulinema

A

Bronchiectasis
Chronic pulmonary insufficiency

19
Q

Most common clinically significant antibody deficiency
Deficiency in B and T cells
Normal CBC
Recurrent respiratory and GI infections
Autoimmune diseases

Management

A

Common variable Immunodeficiency (CVID)

IVIG

20
Q

Complications of CVID

A

Lymphoma (EBV-associated)

21
Q

Disruption of B cell differentiation
Defect in CD40 (B cells will not differentiate)
Otitis
Sinopulmonary infection diarrhea
Opportunitistic infections
Lymphoid hypertrophy

Management

A

X-linked Hyper IgM syndrome

T cell abnormality prevents conversion of IgM to IgG

IVIG

22
Q

PCP in absence of HIV

A

Hyper IgM syndrome

23
Q

Eosinophilia
Eczema
Elevated IgE
Recurrent sinopulmonary/skin infections
Thrush
Skeletal abnormalities

Management

A

Job (Hyper IgE) syndrome

Antibiotics and steroids

24
Q

Decreased T-helper function
Severely low IgG
Outgrow by 3-6 years

A

Transient hypogammaglobulinemia of Infanxy

25
Q

Ataxia
Conjunctival discoloration
Frequent sinus infections
Developmental regression

A

Ataxia Telangiectasia

Autosomal recessive

26
Q

Conotruncal cardiac anomalies and VSD
Abnormal facies
Thymic aplasia and hypoplasia
Tetany
Cleft palate
Hypoparathyroidism

A

22q11 deletion syndrome

27
Q

Best therapeutic approach for DiGeorge

A

Thymic transplantation

28
Q

Complete absence of B and T cell function
FTT
Chronic diarrhea
Recurrent opportunistic infection
Low WBC

Management

A

Severe Combined Immunodeficiency (SCID)

T cell receptor excision circles

Supportive. BMT

29
Q

Eczema
Thrombocytopenia/unusual bleeding
Cellular immunodeficiency
Recurrent sinopulmonary infections
Small platelets
Encapsulated bacteria
Opportunistic infection

A

Wiskott-Aldrich t

30
Q

Management and complications of wiskott-aldrich

A

Supportive
BMT. HSCT.

Lymphoma (most common cause of death)

31
Q

C1-C4 deficiency

A

Recurrent sinopulmonary infection due to encapsulated bacteria

32
Q

C5-C9 deficiency

A

Recurrent Neisseria infection
Increased risk of meningitis

33
Q

Blood streaks in poop
Growing well
Non-IgE mediated

A

Protein-induced proctitis

34
Q

Reduced C1 inhibitor and C4 levels

A

Hereditary angioedema

35
Q

Congenital telangiectatic erythema
Long face
Large protruding ears

A

Bloom syndrome

36
Q

Drug association with IgA bullous dermatosis

A

Vancomycin

Laughing Your Way (34 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions