restrictive lung disease

Question 1

pirfenidone

Answer 1

main drug for IPF
anti inflam, antiox, anti fibrosis

Question 2

what is IPF

Answer 2

idiopathic pulmonary fibrosis

Question 3

what is myesthenia gravis

Answer 3

nmj situation autoimmune
ocular to start with but can be all over

Question 4

sarcoidosis

Answer 4

self limiting normally
multi organ granulomas

Question 5

what treatment if sarcoidosis symptomatic

Answer 5

steroids

then methotrexate
folic acid
mycophenolate which are steroid sparing

Question 6

recfractory sarcoidosis tx

Answer 6

infliximab

Question 7

mech of infliximab

Answer 7

tnf alpha inhibitore

Question 8

why IPF prognosis so poor

Answer 8

very late diagnosis and idiopathic

Question 9

risk factor for IPF

Answer 9

GORD

Question 10

what do you see on IPF HRCT

Answer 10

honeycombing

Question 11

diagnostic test for IPF

Answer 11

DLCO

Question 12

DLCO parameters

Answer 12

lung surface x rate of capillary CO uptake

Question 13

what is pathologicAL DLCO

Answer 13

<70%

Question 14

IPF auscultation

Answer 14

crackles on inspiration

Question 15

other than pirfenidone, what other tx

Answer 15

pulmonary rehab
Lung Tx
long-term O2