kidneys Flashcards
muscles in afferent and/or efferent arterioles of kidney?
yes
bowman’s space becomes
proximal tubule
renal bloodflow amount/m and % total
1.5l/m 20% total bloodflow
normal gfr is
~120ml/min
what’s in the box
macula densa/jga
endothelium in glomerulus
fenestrated
order of things in glomerulus
plasma, fenestrated endothelium, basement membrane, podocyte
podocytes are tied together by which 2 proteins?
podocin and nephrin
basement membrane has which charge
-
charge of albumin
-
what molecular weight can’t get through gbasement membrane
5200daltons ish
can albumin get through gbm? why?
no. too big and negative charge
what is substance measured in eGFR
creatitine
regarding serum creatinine - musclular person vs malnourished
high but no problem
low but could be a problem
apical side of tubular cells faces..
wee tube lumen
tubular cells held together by..
tight junctinos
most absorption in PCT uses which gradient
sodium
what gets pulled in via symporters in pct (3)
glucose
amino acids
phosphate
renal glycosuria
sglt2 doesn’t work
Bartter type 1 disease imitates which drug
frusemide
pct role
bulk of reabsorption
what is renal threshold
carriers get saturated so stuff gets peed out eg glucose in diabetes
what exists to turn the medullary pyramids into a desert
loop of Henle
A pelvis
B pyramid
C papilla