cardiomyopathies Flashcards
what is primary cardiomyopathy
problem in the heart itself
what is 2ary cardiomyopathy
other disease etc causing problem
what is happening here? what stain
fibrosis - necrotic cardiomyocytes are replaced by collagen
trichrome - stains collagen blue
2 mechanism compensate for HF
RAAS
SNS
what effect on Mitral valve LV hypertrophy
leaflets pulled out of shape so regurgitatio
what causes palpitations in HF
arrhythmias
worst risk of hypertrophic cardiomyopathy
sudden death in young and athletes
what causes hypertrophic cardiomyopathy
genes.
normally one mutation
inheritance mode hypertrophic cardiomyopathy
autosomal dominant
where is hypertrophic region in hypertrophic cardiomyopathy
septum
what signs hypertrophic cardiomyopathy (4)
Jerky pulse, double apex beat, systolic thrill at left sternal edge, harsh ejection systolic murmur.
tamponade signs
elevated JVP
tachycardia
muffled heart sounds
dyspnoea
hypotension
