Respiratory system 1 Flashcards

1
Q

what are the 4 primary functions of the respiratory system (4)

A
  1. exchange of gases between the atmosphere and blood
  2. homeostatic regulation of body pH
  3. protection from inhaled pathogens and irritating substances
  4. vocalization
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2
Q

what is vocalization

A

moving air across vocal cards for sound

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3
Q

how does air exchange occur

A

bulk flow from a region of high pressure to low pressure

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4
Q

what creates the pressure gradient in the respiratory system

A

muscular pump

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5
Q

what kind of muscle is the muscular pump

A

all skeletal

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6
Q

what is resistance in the respiratory system influenced most by

A

diameter of tubes

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7
Q

what is external respiration

A

the movement of gases between the environment and the cells within the body
basically everything but actual cellular respiration

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8
Q

what are the 4 steps to external respiration

A
  1. atmosphere to lung (breathing)
  2. lung to blood
  3. transport of gases in the blood
  4. blood to cells
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9
Q

what does external respiration require

A

coordination between the respiratory system and the cardiovascular system

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10
Q

What are 4 upper airway structures?

A

Pharynx
Nasal cavity
Larynx
Esophagus

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11
Q

What are some lower respiratory system structures

A

Trachea
Lungs
Diaphragm

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12
Q

What are alveoli

A

Sacks that serve as exchange place

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13
Q

What lung is slightly larger?

A

Right lung

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14
Q

Why is the left lung smaller than the right one?

A

The left lung has a cardiac notch

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15
Q

What is the pleural sac

A

Double membrane surrounding the lung
Each lung has its own

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16
Q

What is the visceral pleura connected to

A

The outside surface of the lungs

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17
Q

What is the parietal pleura connected to?

A

The inside surface of the thoracic cavity

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18
Q

What lung has 3 lobes

A

Right

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19
Q

What lung has 2 lobes

A

Left

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20
Q

What does the pleural cavity do? (2)

A

Creates a moist slippery surface
Holds lungs fight to thoracic wall

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21
Q

Are the lungs attached to anything?

A

No, the pleural cavity liquid helps with it not recoiling

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22
Q

What connects lungs to the external environment

A

Airways

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23
Q

What’s the pathway of airflow into the body

A

Pharynx
Larynx
Trachea

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24
Q

What’s the starting airway for lower respiratory system?

A

Trachea

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25
What conditions air before it reaches alveoli
Upper airways and bronchi
26
Why is conditioning air and filtering out foreign material more efficient with nose breathing?
Shape of nasal airway tends to cause particles to embed in the back of the pharynx and slide down to the esophagus
27
What 3 processes are more efficient with nose breathing?
1. Warming air to body temperature 2. Adding water Vapor 3. Filtering out foreign material
28
Where is air filtered?
Trachea and bronchi
29
What are the two types of cells in the trachea?
Ciliates epithelial cells Goblet cells
30
What cell produces saline?
Ciliates epithelial cells
31
What do ciliated epithelial cells produce?
Saline
32
What cells produce mucus
Goblet cells
33
What do goblet cells produce?
Mucus
34
What happens to substances in the trachea?
Get stuck in mucus layer and ultimately end up in stomach to be neutralized
35
What does mucus contain?
Immunoglobins
36
What do the cilia on epithelial cells do? What is this process called?
Push mucus towards the pharynx. Mucocilliary escalator
37
What's the layer of cells in trachea? Starting at the lumen of the trachea
Lumen Mucus layer Saline layer Cilia epithelial cells Goblet cells
38
What is necessary for mucocillary escalator function?
Saline
39
What do cilia do in the mucocillary escalator function? What does the saline layer do?
Cilia moves the saline Saline layer pulls mucus layer towards the pharynx
40
What would happen without the saline layer in the mucocillary escalator function?
Cilia would become embedded in thick mucus and become unable to move
41
What drives the production of saline within airways?
Cl
42
What channel allows Cl to enter the lumen?
CFTR channel
43
What gene mutation causes cystic fibrosis
The gene that codes for CFTR
44
What is cystic-fibrosis?
Reduced saline so trachea gets full of mucus
45
Where is the site of gas exchange
Alveoli
46
Where are alveoli?
Clustered at the ends of bronchioles
47
What are alveoli covered in?
Pulmonary capillaries Heavily vascularized
48
Why is there a short distance from capillary to alveoli?
Reduces diffusion space for gas exchange
49
What are the 3 cell types within the walls of alveoli
Type 1 alveolar cell Type II alveolar cell Alveolar macrophage
50
What are the cells that take up 95% of alveolar surface area
Type l alveolar cells for gas exchange
51
What are type l alveolar cells for?
Gas exchange
52
Where in the airway does airflow have the highest velocity?
Trachea
53
what do type II alveolar cells do
influence the thin layer of fluid between the capillaries and the alveoli
54
what do alveolar macrophages do
help with infections within alveoli
55
how long does it take for blood to get through pulmonary circuit
about 6 seconds
56
what is an example of a very low volume circuit
pulmonary circuit
57
how much of the total blood volume does the pulmonary circuit contain
0.5 L or about 10%
58
what is flow
the volume of fluid over a certain amount of time
59
whats unique about the pulmonary circuit
it has a high flow rate but is a low pressure circuit
60
what is the low pressure in the pulmonary circuit due to
low resistance (high cross sectional area) and minimal filtration