Renal 4 Flashcards
What is reabsorption in the proximal tubule dependent on
Active transport of Na
What is inulin
A polysaccharide that gets completely filtered and not reabsorbed
Filtered load of insulin = ___________ load of insulin
Excreted
What’s the ideal substance for measuring someone’s GFR
Inulin
Where would we see the use of inulin
Experimentally
What’s a common substance used to measure GFR that is created in the body?
Creatine
Why isn’t creatine a perfect measure of GFR
It is freely filtered, but it is secreted in a very small amount
Creatinine clearance will slightly _________ GFR
Overstimulate
What does clearance help determine
Net renal handling
The secretion of organic molecules via oat transporters is an example of
Tertiary active transport
What is renal clearance
How much plasma is completely cleared of the solute
How is renal clearance measured from someone
Urine and a blood sample
Filtered load of X =
[X] plasma X GFR
What is urea clearance an example of?
Net reabsorption
Penicillin is an example of
Net secretion
If clearance is 150 ml/min, what does that mean
150ml of plasma are being completely cleared of penicillin each minute
What does comparison of clearance values tell you
Net handling of a solute
Filling of the bladder activates stretch receptors initiating the ____________
Micturition reflex
What is the micturition reflex
Peeing
What undergoes rhythmic contractions due to pacemaker cells
Ureters
What initiates the micturition reflex
Stretch receptors due to filling of bladder
What kind of muscle is the bladder
Smooth muscle / detrusor muscle
What kind of muscle is the internal sphincter
Smooth muscle
What kind of muscle is the external sphincter
Skeletal muscle
