Respiratory Infections II (26) Flashcards
Dr. Erol
What are the 4 systemic dimorphic fungi?
b. dermatitidis
c. immitis
h. capsulated var. capsulatum
cryptococcus neoformans
In most cases, a respiratory infection with systemic dimorphic fungi is _____, resolves _____, and confers ____ to reinfection
asymptomatic
resolves rapidly
confers resistance to reinfection
What are the properties of 3 of the 4? List them
they are thermally dimorphic
- blastomyces dermatitidis
- coccidiodes immitis
- histoplasma capsulate var. capsulatum
Cryptococus neoformans is a _____
yeast
Disease associated with systemic dimorphic fungi tend to be ______
restricted to certain geographic regions
What is the ecology, saprobic form, and parasitic form of blastomyces dermatitidis?
ecology: slightly acidic soils
saprobic: hyphae, oval to pyriiform
parasitic: unencapsulated yeasts with thick refractive double walls
What is the ecology, saprobic form, and parasitic form of coccidioides immitis?
ecology: alkaline desert soils
saprobic form: barrel-shaped arthroconidia alternating with thin-walled empty cells
parasitic: spherules
What is the ecology, saprobic form, and parasitic form of histoplasma capsulatum?
ecology: humid, highly nitrogenous soils
saprobic: hyphae
parasitic: tiny, ovoid budding yeasts with narrow bases
What is the name of the disease blastomyces dermatitidis causes?
blastomycosis
Who is blastomycosis common in?
humans, dogs, cats
What are the gross lesions for blastomycosis?
gray to yellow areas of pulmonary consolidation
nodules in lungs and thoracic lymph nodes
nodular pyogranulomas
Where does blastomycosis go?
lungs —> skin, eye, bones
If blastomycosis progresses, ______ develops
pyogranulamatous inflammation
What are common clinical signs of blastomycosis?
coughing, dyspnea, dry and harsh lung sounds
lameness
lymphadenopathy
skin lesions
What clinical sign of blastomycosis is pronounced in cats?
skin lesions
A dog exhibiting weight loss and labored breathing was thought to have gray to yellow areas of pulmonary consolidation and nodules in lungs. What is the causative agent and disease?
blastomyces dermatitidis
blastomycosis
A dog exhibiting draining lesion of the nose has labored breathing.
blastomyces dermatitidis
blastomycosis
What is the distribution of blastomycosis?
B. dermatitidis - present world-wide
What is one of the principal systemic mycoses?
b. dermatitidis - blastomycosis
What is the geographical distribution of blastomycoses?
Ohio, Missouri, Tennessee, Mississippi River valleys
How does blastomycoces dermatitidis infect the host?
aerosolized mycelial fragments or spores from the environment are inhaled and deposited in alveoli of a susceptible host
What is the morphology of blastomyces dermatitidis?
spherical, thick-walled, large broad-based budding yeast cells