Miscellaneous Infections II (37) Flashcards
Dr. Erol
Describe mycoplasma spp.
What is the usual habitat for mycoplasma spp.? Ureaplasma spp.?
are found on mucosal surfaces of conjunctiva, nasal cavity, oropharynx, intestinal, and genital tracts
Where are hemotropic mycoplasma found?
surface of erythrocytes
How do you differentiate mycoplasmas?
require enriched media to grow
differentiated by- host specificity, colonial morphology, requirement for cholesterol, biochemical profile, serological methods, PCR
Mycoplasma is urease-[positive/negative], and ureaplasma is urease-[positive/negative]
mycoplasma: urease-negative
ureaplasma: urease-positive (think cause it has urease in the name)
What are suitable specimens for mycoplasma?
mucosal scrapings, tracheal exudates, aspirates, pneumonic tissue, mastitis milk, joint and body fluids
How do you identify mycoplasma spp.?
fried egg microcolonies
What is this?
unstained mycoplasmal microcolonies
What is the pathogenesis of mycoplasma?
do not appear to produce toxins or invasions
production of H2O2
adhesion proteins
similarity between some mycoplasmal and host proteins - could be responsible for immune-mediated injury
How does mycoplasma affect cells?
impair phagocytic functions
antigenic variation to escape from immune system
immune-mediated injury
Clinical infections of mycoplasma are often implicated in disease of ______
mucosal surfaces
What are factors of mycoplasma infection?
extremes of age, stress, intercurrent infections, exacerbation of other diseases
respiratory diseases in farm animals and poultry
What is the causative agent of contagious bovine pleuropneumonia?
m. mycoses subsp. mycoides
What is the causative agent of mastitis, pneumonia, and arthritis in cattle?
m. bovis
Look at mycoplasma species regarding sheep and goats
What are the mycoplasma species in pigs?
What are the mycoplasma species in chickens and turkey?
What are the mycoplasma species of cats?
What is mycoplasma bovis?
an emerging cause of respiratory disease and arthritis in feedlot cattle and in young dairy calves
M. bovis has been associated with _____ in young calves and a syndrome involving chronic ____ and _____ in feedlot cattle
otitis media
chronic pneumonia and polyarthritis