Infections of the Skin II (4) Flashcards
What are characteristics of staphylococcus?
facultative anaerobic
gram-positive cocci
Which staphylococci are coagulase positive?
s. aureus
s. pseudintermedius
s. hyicus
Which staphylococci are coagulase negative?
s. epidermis
Which staphylococci are resident?
s. epidermis
How does staphylococcus infect the dermis once the epidermis is damaged?
binding to the host’s extracellular matrix (through ECM-binding proteins)
What virulence factors/mechanisms do staphylococcus sp. have that help in survival, multiplication, and spread?
resist phagocytosis - capsule and clot formation
survive within phagocytotic cells
proteases digest host tissue and damage skin
How do proteases help in staphylococcus spread?
digest host tissue and damage skin
What are the exotoxins for staphylococcus?
leukocidin
hemolysin
coagulase
In staphylococcus, you usually see mixed bacterial infections, as they are the primary invaders, and the production of _____ allows ______
exotoxins
allows secondary invasion by other bacteria
How do you treat staphylococcus?
address the underlying/predisposing issues
antibiotics
What is another word for greasy pig disease?
exudative epidermitis
What is greasy pig disease caused by? It is generally [contagious/non-contagious]
staphylococcus hyicus
contagious - HIGHLY
What is greasy pig disease characterized by?
excessive sebaceous secretion, exfoliation, and exudation on the skin surface
T/F: Pigs that have exudative epidermitis are highly pruritic
FALSE - are non-pruritic and have a greasy exudate
How does s. hyicus enter the skin?
bite wounds - appears unable to penetrate intact skin