Respiratory Drugs

Question 1

What drug is a short-acting B2 adrenergic agonist and is used for the quick relief of asthma symptoms and bronchospasm?

Answer 1

Albuterol

Question 2

What drug is a long-acting B2 adrenergic agonist and has a long duration of action, providing bronchodilation for at least 12 hours and should be used only in combination with an asthma controller medication?

Answer 2

Salmeterol

Question 3

What are the drugs of choice for long-term control in patients with any degree of persistent asthma and directly targets underlying airway inflammation by decreasing the inflammatory cascade?

Answer 3

Corticosteroids

Question 4

What do corticosteroids inhibit the release of?

Answer 4

Arachidonic acid

Question 5

What are products of the 5-lipoxygenase pathway of arachidonic acid metabolism and part of the inflammatory cascade and prevention of exercise induced bronchospasm?

Answer 5

Leukotrienes B4

Question 6

What constricts bronchiolar smooth muscle, increase endothelial permeability, and promote mucus secretion?

Answer 6

cysteinyl leukotrienes

Question 7

What drug is a prophylactic anti-inflammatory agent that inhibits mast cell degranulation and release of histamine and is available as a nebulized solution for use in asthma?

Answer 7

Cromolyn

Question 8

What cholinergic antagonist drug may be useful in patients who are unable to tolerate a SABA or patients with concomitant COPD?

Answer 8

Ipratropium

Question 9

What drug is a bronchodilator that relieves airflow obstruction in chronic asthma and decreases its symptoms?

Answer 9

Theophylline

Question 10

Does theophylline have a large or narrow therapeutic window?

Answer 10

Narrow

Question 11

What drug is a recombinant DNA-derived monoclonal antibody that selectively binds to IgE?

Answer 11

Omalizumab

Question 12

What is the foundation therapy for COPD?

Answer 12

Inhaled bronchodilator

Question 13

What long-acting agents are the first-line treatment of COPD?

Answer 13

LABAs and tiotropium

Question 14

What is an oral phosphodiesterase-4 inhibitor used to reduce exacerbations in patients with severe chronic bronchitis and is NOT a bronchodilator?

Answer 14

Roflumilast

Question 15

What is the most effective medications for treatment of allergic rhinitis?

Answer 15

intranasal corticosteroids

Question 16

What drug suppresses the cough reflex through peripheral action and anesthetizes the stretch receptors located in the respiratory passages, lungs, and pleura?

Answer 16

Benzonatate

Question 17

What drug is a leukotriene modifier that blocks the effects of cysteinyl leukotrienes?

Answer 17

Montelukast

Question 18

What drug is used for cough suppression and is a synthetic derivative of morphine that has no analgesic effects?

Answer 18

Dextromethorphan

Question 19

What drug is used for cough suppression and is an expectorant, is available as a single-ingredient formulation and is also a common ingredient in combination products with codeine or dextromethorphan?

Answer 19

Guaifenesin

Question 20

Where is Theophylline metabolized?

Answer 20

Liver