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Pharmacology > GI medications > Flashcards

GI medications Flashcards

1
Q

What are over the counter medications used to work in the stomach to neutralize gastric acid?

A

Antacids

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2
Q

What symptoms do antacids relieve?

A

Acid indigestion, heartburn, dyspepsia, or GERD

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3
Q

What antacid causes systemic acidosis, has a high sodium content, and is found in Alka Seltzer?

A

Sodium Bicarbonate

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4
Q

What over the counter medication contains Calcium Carbonate?

A

TUMS

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5
Q

What is the most widely prescribed drugs worldwide and is the most potent inhibitors of gastric acid secretion?

A

Proton Pump Inhibitors

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6
Q

What do Proton Pump Inhibitors irreversibly inactivate?

A

H/K ATPase in the parietal cell

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7
Q

What are PPIs rapidly activated by?

A

protonation

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8
Q

What vitamin do PPIs reduce the absorption of?

A

Vitamin B12

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9
Q

What minerals do PPIs reduce the absorption of?

A

Calcium and Magnesium

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10
Q

What drug do PPIs interfere with the activation of?

A

Clopidogrel

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11
Q

What anti-ulcer drug will polymerize to form a sticky, viscous material that binds to exposed proteins in the ulcer crater where it will form a protective barrier?

A

Sucralfate

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12
Q

When should Sucralfate be taken to be most effective?

A

Before a meal

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13
Q

What mineral can form non absorbable complexes with phosphate and a variety of drugs?

A

Aluminum

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14
Q

What drug increases mucus production, may also reduce acid secretion, and is used to induce abortions?

A

Misoprostol

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15
Q

What is Misoprostol used to prevent?

A

NSAID induced ulceration

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16
Q

What drugs are used to treat undesirable toxins, acids, and gases in the GIT and must be administered right after the ingestion of the toxic substance, as charcoal can only bind with drugs or poisons that have not been absorbed yet?

A

Adsorbent drugs

17
Q

What is the most common clinical adsorbent ?

A

Activated Charcoal

18
Q

What drug is a antiflatulant and changes surface tension of gas bubbles and causes collapse of foam bubbles, thus allowing easier passage of gas and preventing gas pockets in gastrointestinal tract?

A

Simethicone (Gas-X)

19
Q

What reduces the effectiveness of pancreatic enzymes and should not be given at the same time?

A

Antacids

Pharmacology (21 decks)

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