Diabetic Drugs

Question 1

What type of diabetes is insulin dependent and is selective beta cell destruction and severe or absolute insulin deficiency?

Answer 1

Type 1

Question 2

What type of diabetes is non-insulin dependent diabetes and characterized by tissue resistance to the action of insulin combined with a relative deficiency in insulin secretion

Answer 2

Type 2

Question 3

Which type is prone to diabetic ketoacidosis OR death?

Answer 3

Type 1

Question 4

Which type is prone to non-ketotic hyperosmolar coma ?

Answer 4

Type 2

Question 5

T/F: All patients with diabetes should be vaccinated against Streptococcus pneumoniae (once) and influenza virus (annually)

Answer 5

True

Question 6

What medications are used to prevent complications of diabetes?

Answer 6

ACE inhibitors/ARBs, statins, & aspirin

Question 7

What drug is a Biguanide and is the first line therapy of DM?

Answer 7

Metformin

Question 8

Does Metformin release insulin?

Answer 8

NO

Question 9

T/F: Metformin is not metabolized and excreted by kidney as active compound

Answer 9

True

Question 10

What does Metformin block?

Answer 10

Gluconeogenesis therefore impairing lactic acid metabolism

Question 11

What are the key adverse effects of Metformin?

Answer 11

Diarrhea, B12 deficiency, and lactic acidosis

Question 12

What is the first GLP-1 agonist that became available that increases insulin release, suppression of postprandial glucagon release, slows gastric emptying, and central loss of appetite?

Answer 12

Exenatide

Question 13

What may Exenatide cause?

Answer 13

Pancreatitis