Drugs 1 Flashcards
What objective is to produce sleep, eliminate pain and reflex activity, and cause relaxation of skeletal muscles in preparation for surgery and interferes with functioning of ion channels by affecting protein and/or lipid membranes?
General Anesthetics
What are known as natural pain killers?
Endogenous Opioid peptides
What is known to inhibit the communication of the pain signal primarily in the brain stem and is otherwise known as endogenous morphine?
Endorphins
What drugs are naturally derived from opium such as heroin, morphine, and codeine?
Opiates
What is a family of opiates including natural, synthetic, and semisynthetic drug that binds to the brain’s opioid receptor that include oxycodone and hydrocodone?
Opioids
T/F: all opiates are opioids, not all opioids are opiates
True
What drug is effective for all pain especially dull pain, elevates pain threshold, and can cause respiratory depression leading to death and it’s antidote is Naloxone/Naltrexone?
Morphine
What is a competitive antagonist at an opioid receptor?
Antidote
What non-narcotic analgesic is an anti-inflammatory , decreases platelet aggregation, increases bleeding time, inhibits prostaglandin synthesis in the periphery, elevates pain threshold in thalamus, and has prostaglandins sensitize pain receptors?
Salicylates
What non-narcotic analgesic is similar to aspirin and does not cause GI bleeding, uric acid retention, does not affect platelets or bleeding time, it is NOT an anti-inflammatory. Also contains Acetylcycteine which minimizes damage to liver in cases of overdose?
Acetaminophen
What is effective only on body temperature abnormally elevated by pyrogens, decreases prostaglandins, but has no effect on hyperthermia caused by exercise, heat stroke, or exhaustion?
Antipyretics
What are psycholeptic drugs that suppress anxiety and modify disturbed behavior at doses that are not markedly hypnotic?
Tranquilizers
What kind of drugs are for mania-depression and bipolar depression?
Antimanics
What increases release of catecholamines and blocks reuptake of adrenergic neurotransmitter?
Amphetamines
What anti-depressant drug inhibits serotonin uptake?
Fluoxetine