Respiratory Flashcards

1
Q

Name the order of stages of respiratory development and the weeks

A

embryonic (4), pseudoglandular (5-16), canalicular (16-26), saccular (26-birth), alveolar (32-birth)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Malformations associated with Potter sequence

A

bilateral renal agenesis, pulmonary hypoplasia, diaphragmatic hernia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

collapsing pressure =

A

2*tension/radius

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

goblet cells end at this level in lung

A

end of bronchi

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

cartilage ends at this level in lung

A

end of bronchi

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

smooth muscle ends at this level in lung

A

terminal bronchioles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

pseudostratified epithelium ends at this level in lung

A

ends with terminal bronchioles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

inspiratory capacity =

A

inspiratory reserve + tidal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

functional residual capacity =

A

Expiratory Reserve + residual

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

vital capacity =

A

expiratory reserve + tidal + inspiratory reserve

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

physiologic dead space =

A

anatomic ds + alveolar ds
= Vt (PaCO2 - PeCO2) / PaCO2

where little a is arterial

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Va (alveolar ventilation) =

A

(Vt-Vd)*RR

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Oxygen content =

A

1.43HbSaO2 + 0.003PaO2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Resistance (of fluid/air) =

A

8nl/pir4

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Pa/A/v and V/Q in Zone 1

A

PA > Pa > Pv. V/Q = 3

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Pa/A/V and V/Q in Zone 2

A

Pa > PA > Pv. V/Q = 1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Pa/A/v and V/Q in Zone 3

A

Pa > Pv > PA. V/Q = 0.6

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Haldane effect

A

high O2 unloads CO2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Bohr effect

A

high CO2 unloads O2

20
Q

Winter’s formula is used for

A

acidosis only. pH = 1.5*bicarb + 8

21
Q

anterior epistaxis from

A

Kiesselbach plexus

22
Q

posterior epistaxis from

A

sphenopalatine artery, a branch of maxillary artery

23
Q

Reid ratio is relevant in this disease

A

chronic bronchitis

24
Q

ferruginous bodies in this pneumoconiosis

A

asbestosis

25
granulomas in this pneumoconiosis
berylliosis
26
eggshell calcification of hilar nodes in this pneumoconiosis
silicosis
27
tb susceptibility in this pneumoconiosis
silicosis
28
the only pneumoconiosis which affects lower lobes
asbestos
29
these are increased in the serum in those with sarcoid
ACE and Ca2+
30
drugs that cause ILD
bleomycin, busulfan, amiodarone, methotrexate
31
what is Caplan syndrome
rheumatoid arthritis and pneumoconiosis with intrapulmonary nodules
32
mutation in heritable PHTN
loss of function BMPR2
33
what is cyclothorax
pleural effusion due to lymphatic obstruction/injury
34
MCCs lobar pneumonia
s pneumo, legionella, klebsiella
35
MCCs bronchopneumonia
s pneumo, s aureus, h flu, klebsiella
36
MCCs interstitial pneumonia
mycoplasma, chlamydia, legionella, viruses
37
tx lung abscess with
clindamycin usually due to anaerobes (bacteroides, fusobacterium, peptostreptococcus) or s aureus
38
mesothelioma histologic markers
cytokeratin, calretinin
39
stain for neuroendocrine cells
chromogranin A. small cell lung is also neuron-specific enolase-positive
40
paraneoplastic syndromes for small cell lung cancer
cushing, SIADH, Lambert-Eaton, antibodies vs. neurons
41
class of drugs: diphenhydramine, dimenhydrinate, chlorpheniramine
first generation H1 inhibitors
42
class of drugs: loratadine, fexofenadine, deslortadine, cetirizine
second generation H1
43
bosentan MOA
antagonizes endothelin 1. used for PHTN
44
long acting beta agonists for asthma
salmeterol, formeterol
45
MOA montelukast, zafirlukast
block leukotriene receptor CysLT1
46
MOA zileuton
block 5-lipoxygenase pathway to inhibit leukotriene synthesis
47
anti IgE antibody for asthma
omalizumab