Pathology Flashcards

1
Q

Infectious causes of granulomas

A

Mycobacteria, bartonella henselae (cat scratch), listeria (granulomatosis infantiseptica), tertiary syphillis, endemic fungi shistosoma

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2
Q

Autoimmune granulomatous diseases

A

sarcoid, Crohn, PBC, subacute thyroiditis, Churgh-Strauss, GCA, Takyasu, Wegener

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3
Q

Foreign material causing granulomas

A

Berylliosis, talcosis, hypersensitivity pneumonitis

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4
Q

Cancer associated with hypercalcemia

A

Squamous cell carcinomas of various organs (PTHrP) and lymphoma (calcitrol)

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5
Q

Cancer associated with Cushing and SIADH

A

small cell of the lung

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6
Q

Cancer associated with pure red cell aplasia and Good syndrome (hypogammaglobulinemia)

A

thymoma

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7
Q

Cancers assoc. w/ Trousseau and NBTE

A

adenocarcinomas, especially pancreatic

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8
Q

Cancers assoc. w/ anti-NMDA receptor encephalitis

A

ovarian teratoma

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9
Q

Cancers assoc. w/ opsoclonus-myoclonus ataxia syndrome (dancing hands, dancing feet)

A

neuroblastoma in kids, small cell lung cancer in adults

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10
Q

Cancers assoc. w/ paraneoplastic cerebellar degeneration (antibodies vs. Hu, Yo, and Tr in Purkinje cells)

A

small cell lung cancer, gynecologic and breast, Hodgkin lymphoma

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11
Q

cancers assoc. w/ paraneoplastic encephalomyelitis (antiboies vs. Hu in neurons)

A

small cell lung cancer

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12
Q

Cancers assoc. w/ lambert-eaton

A

small cell lung cancer

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13
Q

Cancer-causing HPV strains

A

16, 18

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14
Q

Psammoma bodies seen in…

A

papillary carcinoma of thyroid, serous papilary cystadenocarcinoma of ovary, meningioma, malignant mesothelioma

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15
Q

Breast cancer marker

A

CA 14-3/CA 27-29

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16
Q

Pancreatic adenocarcinoma marker

A

CA 19-9

17
Q

Ovarian cancer serum marker

A

CA 125

18
Q

Cytokines that mediate cachexia

A

TNF-alpha, IFN-gamma, IL-1, IL-6

19
Q

Cancer assoc. w/ ALK onocogene

A

lung adenocarcinoma

20
Q

Cancer assoc. w/ BRAF oncogene

A

melanoma, NHL

21
Q

Cancer assoc. w/ KRAS oncogene

A

colon, lung, pancreatic

22
Q

Cancer assoc. w/ MYCL1 oncogene

A

lung tumor

23
Q

Cancer assoc. w/ MYCN oncogene

A

neuroblastoma

24
Q

cancer assoc. w/ RET oncogene

A

MEN 2a and 2b, medullary thyroid cancer

25
Q

cancer from loss of CDKN2A

A

melanoma, pancreatic cancer (p16, blocks G1 to S)

26
Q

cancer from loss of DCC

A

colon cancer (Deleted in Colon Cancer)

27
Q

cancer from loss of DPC4/SMAD4

A

pancreatic cancer (deleted in pancreatic cancer)

28
Q

Cancer assoc. w/ aflatoxin

A

HCC

29
Q

Cancer assoc. w/ aromatic amines

A

transitional cell carcinoma of bladder

30
Q

Cancers assoc. w/ arsenic

A

liver angiosarcoma, lung cancer, squamous cell carcinoma of skin

31
Q

Cancer assoc. w/ ionizing radiation

A

papillary thyroid carcinoma

32
Q

Cancer assoc. w/ radon

A

lung cancer

33
Q

cancer assoc. w/ vinyl chloride

A

liver angiosarcoma