Respiratiry Disease In Occ Med

Question 0

Serpentine (curly fibers) vs Amphibole (needle-like), which is more carcinogenic?

Answer 0

Needle-like amphibole

Question 1

Common causes of pneumoconiosis ?

Answer 1

Silicosis
Asbestosis
Coal workers’ lung

Question 2

Is cigarette smoke and asbestos synergistic for mesothelioma?

Answer 2

No

Question 3

Does cig + asbestos increase the susceptibility for asbestosis?

Answer 3

Yes

Question 4

Does Cig+ asbestos synergistic for bronchogenic cancer?

Answer 4

Yes

Question 5

RR of lung cancer for

Non- somker+non-asbestos worker as 1, RR of lung cancer for asbestos worker is?

Answer 5

5.2

Question 6

RR of lung cancer for

Non- somker+non-asbestos worker as 1, RR of lung cancer in smokers?

Answer 6

10.8

Question 7

RR of lung cancer for

Non- somker+non-asbestos worker as 1, RR of lung cancer in smokers + asbestos workers?

Answer 7

53.2

Question 8

X-Ray showing tiny round opacities primarily in the upper lung fields and hilar adenopathy, Eggshell calcification of hilar lymph nodes, is characteristic of what agent exposure?

Answer 8

Silicosis

Eggshell calcification of hilar lymph nodes occurs in roughly 20% of cases

Question 9

Ferruginous bodies are associated with?

Answer 9

Asbestosis
But ferruginous bodies are not specific to the asbestos fiber and may result from a number of different types of foreign fibers.

Question 10

Bagasse dust is associated with

Answer 10

Pulmonary fibrosis

Question 11

Which herbicide can cause renal failure and rapid pulmonary fibrosis when ingested?

Answer 11

Paraquat

Often used to control marijuana growth

Question 12

Cotton dust endotoxin

Or dust from other vegetable fibers such as flax, hemp, or sisal

Answer 12

Byssinosis ( Cotton worker’s lung, Cotton bract disease, Mill fever, Brown lung)

Sx dyspnea and chest tightness

Question 13

Ammonia, sulphur dioxide inhalation

Answer 13

Upper airway toxicity

Question 14

Chlorine inhalation

Answer 14

Lower airway toxicity

Question 15

Phosgene, nitrogen dioxide

Answer 15

Terminal airway

Question 16

Irritant gases- water soluble

Answer 16

Primary upper-respiratory irritation

• Ammonia, chlorine, formaldehyde
• Sulfur dioxide

Question 17

Irritant gases-water insoluble agent

Answer 17

Cause parenchymal lung damage, ARDS

Nitrogen oxide
Phosgene

Question 18

Silo-filler’s disease is caused by?

Answer 18

Nitrogen oxides

Question 19

Mechanics that phosgene causes parenchymal lung damage?

Answer 19

Phosgene (COCl2) hydrolyzes in lung to HCl

Question 20

Simple asphyxiants?

Answer 20

Reduce oxygen content.

Eg. CO2, methane, N2

Question 21

Chemical asphyxiants ?

Answer 21

Interfere with cellular metabolism

Eg. CO, cyanide, H2S

Question 22

Hypersensitivity pneumonitis (HP)

Answer 22

• A disease in which your lung become inflamed when you breathe in certain dusts to which you are allergic.
• The dust contains fungus spores from moldy hay or the dropping of birds.
• Most common type of HP is farmer’s lung, from exposure to moldy hay, straw, and grain.

Question 23

Chronic beryllium disease can be indistinguishable from ?

Answer 23

Sarcoidosis

• CXR similar: symmetric infiltrate, opacity es, interstitial scarring, and hilar node enlargement
• Distinguish the two rely on
  
  • history of exposure and
  • use of lymphocyte blast transformation test

Question 24

Phosgene and oxides of nitrogen

Answer 24

• relatively lack of immediate signs
• frequently with delayed reaction
• pt exposed to significant concentration of these agent s should be observed for a minimum of 24 hours