Kidney Toxicant Flashcards

0
Q

After a minimum period of 6-10 years exposion, may develop proximal tubular dysfunction ?

A

Cadmium

B2 microglobulin in the urine

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1
Q

Earliest effect of chronic cadmium exposure is?

A

Proteinuria

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2
Q

Ethylene glycol,

Found in antifreeze

A

Causes an acute tubular necrosis and is usually seen in attempted overdoses

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3
Q

Chronic exposure to cadmium or lead

- both of which are used in welding, soldering, and jewelry-making

A

Causes injury to the proximal tubules and may led to chronic renal failure

  • acute overexposure has been associated with oliguric renal failure
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4
Q

Halogenated hydrocarbons, such as carbon tetrachloride

A

Causes acute tubular necrosis, especially if exposure is via inhalation

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