Resp 1 Part 2 Flashcards

1
Q

Measurements of Expiratory Flow:
These are important measurements because they

Used to test for

A

reflect air flow within
large airways.

increased airway resistance.

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2
Q

Forced Vital Capacity (FVC):

A

Volume of air forcibly

expired after maximal inhalation. ~5 L

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3
Q

Forced Expiration Volume 1 (FEV1):

A

Fraction of FVC

expired during the first second.

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4
Q

Normal FEV1/FVC =

A

0.8 (80%)

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5
Q

FEV1 reflects

A

flow in large airways

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6
Q

FEV1 is

A

80

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7
Q

Eupnea

A

Normal quiet breathing

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8
Q

Hyperpnea

A

Increased rate or volume due to
higher metabolism

Exercise

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9
Q

Hyperventilation

A

Increased rate or volume w/o
increased metabolism

Emotions; blowing up a
balloon

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10
Q

Hypoventilation

A

Decreased alveolar ventilation

Shallow breathing;
asthma; restrictive lung
disease

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11
Q

Tachypnea

A

Rapid breathing rate (usually with
decreased depth)

Panting

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12
Q

Dyspnea

A

Difficulty breathing; air hunger

Various pathologies or
hard exercise

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13
Q

Normal, quiet breathing takes —% of total body energy

A

3-5

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14
Q

The energy requirement

will significantly increase if a patient has a respiratory condition that alters

A

compliance/elasticity and/or resistance

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15
Q

Pulmonary patients may require a

A

50-fold

increase in the amount of energy required to fuel adequate ventilation.

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16
Q

OBSTRUCTIVE DISEASES
• Due to — Airway
Resistance

17
Q

OBSTRUCTIVE DISEASES

examples (4)

A

– Asthma
– Emphysema
– Bronchitis
– Cystic Fibrosis

18
Q

obstructive diseases
Primarily impacts —.
Individuals with obstructive
diseases will breathe (2)

A

expiration

slow and deep

19
Q

RESTRICTIVE DISEASES
Due to — Lung
Compliance

20
Q

RESTRICTIVE DISEASES

example

A

pulmonary fibrosis

21
Q

RESTRICTIVE DISEASES
Primarily impacts —
Individuals with restrictive diseases
will breathe (2)

A

inspiration

fast and shallow.

22
Q

Obstructive Disease: Atopic Asthma

A

IgE Mediated -Type I Hypersensitivity Reaction
An allergen leads to an inflammatory response that causes
bronchospasms that obstruct airflow. Chronic inflammation can
lead to impaired mucociliary response, edema and increased
airway responsiveness.

23
Q

Atopic Asthma tx options (2)

A

Quick-relief medications:
β2 agonists,
anticholinergic agents,
etc.

Long-term medications:
inhaled corticosteroids,
long-acting
bronchodilators, etc.

24
Q

Nonatopic Asthma can occur

with (7)

A
respiratory infections, 
exercise, 
hyperventilation, 
cold air, 
inhaled irritants, 
aspirin and 
other NSAIDS
25
Obstructive Disease: Cystic Fibrosis
Autosomal recessive disorder resulting in defective chloride ion transport (mutation in CFTR ion channel) that results in an abnormally thick mucus that obstructs airways.
26
Cystic Fibrosis tx options (4)
``` • Antibiotics • Chest Physical Therapy (percussion and postural drainage) • Mucolytic agents • Pancreatic enzyme replacement ```
27
CF lungs are prone to infection. Eventually permanent colonization of airways is established and organisms become
more and more antibiotic resistant as patients are on long-term antibiotic therapy.
28
Obstructive Disease: Emphysema
Destruction of elastic fibers & enlargement of airspaces due to destruction of airspace walls.
29
Emphysema leads to (3)
(1) Airway collapse which increase R and decrease F (2) Damage to alveolar membrane so decrease gas exchange. (3) decrease Elasticity and increase Compliance
30
Restrictive Respiratory Diseases
Any pulmonary problem that limits lung | expansion (decreased lung compliance)
31
Restrictive Respiratory Diseases: | Tissue injury leads to
chronic inflammation and the normal architecture of the lungs is disrupted and is replaced with scar tissue/fibrosis (the collagen fibers decrease lung compliance)
32
Restrictive Respiratory Diseases: Low compliance Patient finds it much more difficult to ---
inhale
33
Restrictive Respiratory Diseases: | Work of breathing increases
Patient breathes fast and shallow. Because shallow breaths decrease alveolar ventilation there is decrease gas exchange. Includes: Pulmonary Fibrosis (idiopathic, drug- induced, environmental), pneumonia, pulmonary
34
Restrictive Respiratory Diseases: | signs and symptoms (3)
```  Increased respiratory rate  Chronic cough (dry, non- productive)  Polycythemia due to hypoxia ```