Nervous System Flashcards

1
Q

The Nervous System

A

One of the two major control systems of the body mediating systemic homeostatic processes

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2
Q

skipped

what homeostatic processes does the NS mediate? (4)

A

muscle contraction
integration of blood oxygen, carbon dioxide, and pH levels via respiratory activity
regulation of volumes and pressures in the circulation via cardiovascular and urinary function
digestive system motility and secretion

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3
Q

the NS works along with — to Maintain Systemic

Homeostasis

A

Endocrine System (ES)

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4
Q

NS is — fix to homeostatic disturbance and ES is —

A

quick

slower long term maintenance

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5
Q

NS Functional unit =

A

Neurons

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6
Q

Neuroglia =

A

support cells for neurons

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7
Q

NS uses a combination of (2) to

communicate information around body

A

chemical and electrical signals

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8
Q

dendrites are simulated by (2)

A

environmental changes or the activities of other cells

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9
Q

cell body

A

contains the nucleus and mitochondria, ribosomes, and other organelles and inclusions

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10
Q

axon

A

conducts nerve impulse (AP) toward synaptic terminals

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11
Q

synaptic terminals affect

A

another neuron or effector organ (muscle or gland)

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12
Q

nissl bodies

A

clusters of ribosomes found in the cell body

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13
Q

Many neurons have axons

that are —

A

myelinated

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14
Q

— formed by neuroglia cells

A

Internodes

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15
Q

– form myelin for axons in CNS

A

Oligodendrocytes

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16
Q

– form myelin for axons in PNS

A

Schwann cells

17
Q

Internodes separated by small
segments of axon not covered
in myelin –

A

Nodes of Ranvier

18
Q

function of Nodes of Ranvier

A

Speed up the rate of nerve impulse conduction (Saltatory conduction)

19
Q

types of neurons (structural classification) (4)

A

anaxonic
bipolar
pseudo unipolar
multipolar

20
Q

Types of Neurons (Functional Classification) (3)

A

sensory
motor
interneurons

21
Q

Sensory Neurons (pseudounipolar neurons, bipolar) (4)

A

Afferent division of PNS
Carry sensory information from reflex receptor to CNS
Dendrites/Cell body in PNS
Axons typically myelinated and extend into CNS

22
Q

Motor Neurons (Multipolar neurons) (4)

A

Efferent division of PNS
Carry motor commands from CNS to EFFECTORS
Dendrites/Cell body in CNS
Axons typically myelinated, extend into PNS and synapse
with effectors

23
Q

Interneurons (Multipolar, Anaxonic) (3)

A

Found only in the CNS
Carry information from one neuron to another
Integration

24
Q

Information flows in

A

one direction

25
Q

Action Potentials (AP): (5)

A

–Always the same (depolarization followed by repolarization) with no change in strength or size as they travel along the membrane
–All-or-none
–Triggered at Axon Hillock when Threshold Potential reached (Vm at which AP triggered; typically around -50mV))
–Always propagates along cell membrane of axon from axon hillock toward axon terminals
–Relatively fast changes in Vm

26
Q

Graded Potentials (GP): (3)

A

–Small changes in membrane potential of variable strength/amplitude
–Only travel a short distance along membrane and lose strength as they travel
–Often last longer than APs

27
Q

examples of GP (2)

A

EPSP

IPSP

28
Q

EPSP

A

Excitatory postsynaptic potentials (depolarizations); moves Vm
towards threshold potential; increases likelihood of AP

29
Q

IPSP

A

Inhibitory postsynaptic potentials (hyperpolarizations); moves Vm away
from threshold; decreases likelihood of AP

30
Q

Depolarization

A

Vm becomes more positive (less

negative). EPSPs

31
Q

Repolarization

A

Vm returns to resting value

32
Q

Hyperpolarization

A

Vm becomes more negative than resting. IPSPs

33
Q

Which ion channels, if

opened, cause an EPSP? (2)

A

Na

Ca

34
Q

Which ion channels cause an IPSP? (2)

A

K closed

Cl open

35
Q

skipped

Example of a Graded Potential becoming an Action Potential in a Neuron (graph, A-F)

A

A. Resting Membrane Potential
B. EPSP depolarizes membrane
C. EPSP reaches threshold and causes voltage-gated Na+ channel to open—transition from graded
potential to action potential (axon hillock)
D. Depolarization; Na+ moves into the cell through open Voltage-gated (VG)-Na+ channels. Activated via positive feedback (see slide 16).
E. VG Na+ channels close & slow voltage-gated K+ channels open
F. Repolarization; K+ moves outside of the cell through open VG K+ channels
G. Hyperpolarization; VG K+ channels still open
H. Voltage-gated K+ channels close
A. Resting membrane potential

36
Q

Activation gate

A

Closed
at resting Vm, quickly
opens at threshold
depolarization

37
Q

Inactivation gate

A

Open
at resting Vm, slowly
closes at threshold
depolarization

38
Q

Voltage-gated K+ channel:

A

Single voltage gate begins to open
at threshold, but is slow–delayed by
the same time as the VG Na+
channel’s inactivation gate.