Research - The Eye as a Window to Brain Pathology Flashcards

1
Q

what do the CNS and eye extend from during embryonic development

a.diencephalon
b.ectoderm
c.mesenchyme
d.endoderm

A

a.diencephalon

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2
Q

in which condition is there degeneration of the optic nerve , reactive gliosis and microvascular abnormalities seen on opthalmological assessment

a.stroke
b.ms
c.alzheimers disease
d.parkinsons disease

A

a.stroke

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3
Q

in which condition is there cupping of the optic nerve , rcg loss, rfnl thinning , deterioration in visual acuity and retinal atrophy seen on opthalmological assessment

a.stroke
b.ms
c.alzheimers disease
d.parkinsons disease

A

b.ms

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4
Q

in which condition is there dopamine deficiency, electrophysiological abnormalities, rfnl thinning, swollen neurons seen opthalmalogically and deterioration in visual acuity

a.stroke
b.ms
c.alzheimers disease
d.parkinsons disease

A

d.parkinsons disease

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5
Q

in which condition is there p-tau AB accumulation , RCG loss, rfnl thinning, electrophysiological abnormalities

a.stroke
b.ms
c.alzheimers disease
d.parkinsons disease

A

c.alzheimers disease

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6
Q

av nicking, retinal haemorrhage, arteriolar narrowing are predictors of….

A

stroke

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7
Q

dysfunction of ……….. is suspected to have a central role in the development of cerebral and retinal microangiopathy

a.cerebral hemispheres
b.blood brain barrier
c. nerve cells
d.myelin

A

b.blood brain barrier

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8
Q

disease of blood vessels affecting small blood vessels in the body

A

microangiopathy

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9
Q

………… in retinal nerve fibre layer thickness correlates directly with progression of neurological impairment and with disease duration

a.increase
b.decrease

A

b.decrease

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10
Q

optic neuritis is seen in….

a.stroke
b.ms
c.alzheimers disease
d.parkinsons disease

A

b.ms

inflam of optic nerve causing blurred vision

along with retinal ganglion degeneration

visual acuity and contrast sensitivity are decreased

retinal nerve fibre layer is thinner

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11
Q

patient diagnosed wit optic neuritis what should be done next

a.referred to neurologist for an MS directed evaluation

b.referred to neurologist for a stroke directed risk assessment

c.referred to neurologist for a parkinson directed evaluation

A

a.referred to neurologist for an MS directed evaluation

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12
Q

deterioration in visual acuity , abnormal responses on electrophysiological testing, swelling of photoreceptors and rcg and thinning of the RNFL is seen in what

a.stroke
b.ms
c.alzheimers disease
d.parkinsons disease

A

d.parkinsons disease

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13
Q

RCG atrophy, narrowing of the retinal veins,reduced retinal blood flow , thinner RNFL , retinal dysfunction, accumulation of amyloid beta and pTau in the eye and reduction in the in macular volume is seen in what

a.stroke
b.ms
c.alzheimers disease
d.parkinsons disease

A

c.alzheimers disease

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14
Q

reduction in macular volume as seen in alzheimers correlates with cognitive impairment as measured with which exam

a.montreal cognitive assessment
b.mini mental state exam

A

b.mini mental state exam

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