Physiology - Ascending tracts , sensory receptors, pathways and peripheral pathways Flashcards
afferent
towards CNS
efferent
away CNS
which of these is NOT a somatosense
a.pain
b.temperature
c.touch
d.pressure
e.taste
e.taste
which receptor type is activated by physical compression / stretch
a.mechanoreceptors
b.thermoreceptors
c.electromagnetic
d.chemoreceptors
a.mechanoreceptors
which receptor type is activated by temperature on skin and internally
a.mechanoreceptors
b.thermoreceptors
c.electromagnetic
d.chemoreceptors
b.thermoreceptors
separate cold and hot receptors
which receptor type is activated by light
a.mechanoreceptors
b.thermoreceptors
c.electromagnetic
d.chemoreceptors
c.electromagnetic
which receptor type is activated O2/H+/CO2 in the brainstem and osmolarity in the hypothalamus
a.mechanoreceptors
b.thermoreceptors
c.electromagnetic
d.chemoreceptors
d.chemoreceptors
which type of receptors give rise to pain sensations
a.nociceptors
b.proprioceptors
c.somatosensors
a.nociceptors
which type of receptors give info about joint position and movement
a.nociceptors
b.proprioceptors
c.somatosensors
b.proprioceptors
the area monitored by a single receptor
a.dermatome
b.receptive field
b.receptive field
local membrane depolarisation in a receptor
a.action potential
b.receptor potential
c.membrane potential
d.resting potential
b.receptor potential
may or may not be sufficient to cause an action potential
how is stimulus strength coded
a.number of action potentials
b.frequency of action potentials
c. volume of action potentials
b.frequency of action potentials
phasic response
depending on properties of receptor being stimulated the response of the primary afferent is different
phasic response causes a burst of AP at the onset of the stimulus the frequency soon dissipates despite the stimulus still being present
typical of certain receptors eg pacinian corpuscle
tactile receptors all have channels in the membranes of the receptor nerve endings that are permeable to which ion when they are physically deformed by pressure/pulling
a.calcium
b.potassium
c.sodium
d.iron
e.hydrogen
c.sodium
which tactile receptors have bare dendrites between epidermal cells small fields and act as sole cornea receptors
a.free nerve endings
b.root hair plexus
c.merkels discs
d.laminated pacinian corpuscles
e.ruffini corpuscles
a.free nerve endings
which tactile receptors in the skin have sensory dendrites surrounding the hair follicles and rapidly adapting
a.free nerve endings
b.root hair plexus
c.merkels discs
d.laminated pacinian corpuscles
e.ruffini corpuscles
b.root hair plexus
which tactile receptors in the skin are responsive to fine touch and low frequency with a dendrite network surrounding schwann cells , found within a capsule in the dermis and numerous in sensitive areas eg fingertips , lips
a.free nerve endings
b.root hair plexus
c.meissners corpuscle
d.laminated pacinian corpuscles
e.ruffini corpuscles
c.meissners corpuscle
which tactile receptors in the skin are very sensitive tonic touch receptors with dendrites closely associated with large epithelial cells and very small fields
a.free nerve endings
b.root hair plexus
c.merkel discs
d.laminated pacinian corpuscles
e.ruffini corpuscles
c.merkel discs
which tactile receptors in the skin respond to deep pressure and high frequency vibration and are rapidly adapting mostly found in the fingers and viscera
a.free nerve endings
b.root hair plexus
c.merkel discs
d.laminated pacinian corpuscles
e.ruffini corpuscles
d.laminated pacinian corpuscles
which tactile receptors in the skin have dendrites that are intertwined with collagen fibres in a capsule and respond to skin pressure and distortion
a.free nerve endings
b.root hair plexus
c.merkel discs
d.laminated pacinian corpuscles
e.ruffini corpuscles
e.ruffini corpuscles
which receptors are free nerve endings that detect joint pressure, movement and tension
a.merkel discs
b. baroreceptors
c.golgi tendon organs
d.muscle spindle
e.joint receptors
e.joint receptors
which of these receptors is described as free nerve endings embedded in the walls of major vessels giving information primarily on wall stretch
a. meissners corpuscle
b. golgi tendon organs
c.baroreceptors
d.pacinian corpuscle
e.chemoreceptors
c.baroreceptors
what are the 4 types of receptor as classified by transduction mechanism
mechanoreceptor
chemoreceptor
temperature receptors
electromagnetic receptors
what are the 2 types of receptor when classified by purpose
nociceptor - pain
proprioceptior - body position and movement
what are the 3 types of mechano receptor
somatosensory receptors (skin)
proprioceptors (muscle and joint)
baroreceptors
temperature receptors located where are the major determinant of temperature sensation
a.pituitary
b.hypothalamus
c.skin
d.cerebellum
e.ventricle
b.hypothalamus
which receptors rely on the activity of transient receptor potential (TRP) channels with different TRP channels being activated at different temperatures
a.mechanoreceptors
b.chemoreceptors
c.temperature receptors
d.electromagnetic receptors
e.nociceptors
c.temperature receptors
which TRP channel when activated gives moderate cold sensation at temp below 27 degrees
a.TRPM7
b.TRPM8
c.TRPV3
c.TRPV4
b.TRPM8
which TRP channel when activated gives moderate warm sensation at temp 25 degrees
a.TRPM7
b.TRPM8
c.TRPV3
c.TRPV4
c.TRPV3
which TRP channel when activated gives moderate warm sensation at temp 31 degrees
a.TRPM7
b.TRPM8
c.TRPV3
c.TRPV4
c.TRPV4
which temperature channel is activated by menthol giving it a cooling effect
a.TRPM7
b.TRPM8
c.TRPV3
c.TRPV4
b.TRPM8
pain receptors are free nerve endings tat respond to ….
chemicals associated with damage/ inflammation eg potassium, prostaglandins , ATP , adenosine and 5HT
mechanical stress associated with tissue damage
temperatures above 43 degress and below 18 degrees eg TRP channels
which type of pain receptor axons have slow conduction velocity resulting in a slow pain feeling
a.type A
b.type B
c.type C
d.type D
c.type C
which type of pain receptor axons have a fast velocity conduction and so give a fast pain feeling
a.type A
b.type B
c.type C
d.type D
a.type A
which type of axon conducts fastest
a.small myelinated
b.large myelinated
c.large unmyelinated
d.small unmyelinated
b.large myelinated
which fibres would be responsible for transmitting an aching pain
a.type A
b.type B
c.type C
d.type D
c.type C
slow fibres
the cell body of the primary afferent nerve is located where
a.muscle
b.joint
c.dorsal root ganglion
d.spinal cord
c.dorsal root ganglion
enters the spine via the dorsal root
cell body in DRG outside the spinal cord
the slower axons travel to areas more dorsal in the spinal cord . which lamina does this indicate
a.lamina I and II
b.lamina III and IX
a.lamina I and II
the faster axons travel to areas more ventral/ deeper in the spinal cord . which lamina does this indicate
a.lamina I and II
b.lamina III and IX
b.lamina III and IX
which of these viruses reside in the primary afferent cell bodies in dorsal root ganglion of a certain spinal nerve . when this virus travels to the ends of this afferent nerve it causes pain and blistering in these areas so the rceeptor regions associated with this nerve become visible
a.herpes simplex
b.herpes zoster
c.hepatitis c
d.hepatitis A
e. HIV
b.herpes zoster
chicken pox
referred pain from the myocardium to the left arm is due to the afferents from the myocardium entering the spinal cord at which level associated with the left arm dermatome
a.C4-C7
b.T1-T4
c.T6-T10
d.T12-L1
b.T1-T4
which ascending path carries information from temp, pain, crude touch and pressure receptors as well as tickling and itch sensation
a.spinothalamic tract
b.dorsal column
a.spinothalamic tract
which fibres transmit the information in the spinothalamic tract
a.small
b.large
a.small
slower velocity poor spacial discrumination
after synapsing in the spine which neuron crosses the spine in the spinothalamic tract
a.primary
b.secondary
c.tertiary
b.secondary
then ascends contralaterally to the thalamus of the midbrain
after crossing the spine the secondary neuron ascends ………….. to the thalamus of the midbrain in the spinothalamic tract
a.contralaterally
b.ipsilaterally
a.contralaterally
which neuron travels via the spinothalamic tract to the sensory cortex causing sensation to become concious
a.primary
b.secondary
c,tertiary
d.quaternary
c,tertiary
which ascending pathway carries information from proprioceptors with high discrimination and fast conduction velocity
a.spinothalamic tract
b.dorsal column
c.spinocerebellar tract
b.dorsal column
primary afferents in the dorsal column do not synapse , instead they ascend…
a.contralaterally
b.ipsilaterally
b.ipsilaterally
without crossing the spine
ascend ti dorsal column nucleus in the brain
synapses with 2nd neurone that crosses to the other side within the medulla
primary afferents in the dorsal column synapse with a secondary neuron that crosses to the other side where
a. across the spinal cord
b.the medulla
c.the pituitary
d.the hypothalamus
b.the medulla
where does the secondary neuron ( from the dorsal column) synapse with the tertiary neuron after leaving the medulla
a.thalamus of mid brain
b.hypothalamus
c.cerebellum
d. in the spine
a.thalamus of mid brain
which tract is especially important in control of movement and balance
a.spinothalamic tract
b.dorsal column
c.spinocerebellar tract
c.spinocerebellar tract
somatosensory information arrives in the sensory cortical areas in the postcentral gyrus in which lobe
a.frontal
b.temporal
c.parietal
d.occipital
c.parietal
somatotrophic representation
different parts of the body are represented in different parts of the cortical areas
the somatic sensations from one side of the body are processed by the ………. side of the brain
a.ipsilateral
b.contralateral
b.contralateral
widespread damage of primary afferents can be caused by
a.coagulopathy
b.neuropathy
c. huntingtons
d.parkinsons
b.neuropathy
diabetes, MS, chronic alcohol consumption and chemotherapy can all cause what
a.paralysis
b.ataxia
c.neuropathy
d.aphasia
c.neuropathy
paraesthesia
pins and needles
anaesthesia
numbness
damage of the ascending tracts is usually
a.bilateral
b.unilateral
a.bilateral
damage to the ascending tracts causes what
a.sensory loss of all modalities below the lesion
b. sensory loss to some modalities below the lesion
c.motor loss of all modalities below the lesion
d.motor loss of some modalities below the lesion
a.sensory loss of all modalities below the lesion
some senses lost on one side and other senses lost on the other side indicate what
a.unilateral damage to the ascending tracts
b.bilateral damage to the ascending tracts
a.unilateral damage to the ascending tracts
eg slow growing spinal tumour
which part of the ascending tracts is usually damaged following a stroke
a. primary neurone
b.area of crossing spine
c.from spine /medulla to thalamus
d.from thalamus to cortex
d.from thalamus to cortex
(internal capsule)
causes sensory loss in opposite side of the body
potential paralysis if nearby motor areas are affected