Red Blood Cells Chapter 5 Flashcards
Formed elements of blood include:
Red blood cells
white blood cells
platelets
Formed elements are produced by the _____ bone marrow, which contains stem cells
red
The liquid medium for carrying various substances in the blood
plasma
______ of the plasma is water, while _____ of the plasma consists of salts, ions and organic molecules (glucose, amino acids, gasses, hormones, wastes, plasma proteins).
91%
9%
Salts help maintain the ______ pressure of blood
osmotic
Salt also acts as _____ to help maintain pH
buffers
Plasma proteins acts as a buffer to help keep blood pH around _____
7.4
Plasma proteins are too large to pass through capillary walls, thus they remain in the blood, establishing an ______ pressure
osmotic
Red blood cells
durable and flexible
carries hemoglobin protein
small (6-8 micrometers)
biconcave disks
very abundant
4-6 million red blood cells per microliter
Erythrocytes
How many 02 molecules can one hemoglobin carry?
4
Takes this shape when 02 binds to heme in the lungs
oxyhemoglobin
When 02 is given up it resorts to this former shape
deoxyhemoglobin
____ forms weak covalent bond with heme
____ forms strong covalent bond with heme
Oxygen
CO2
Put these in order
A) Kidney increases production of erythropoietin
B) Low 02 blood level
C) 02 blood level returns to normal
D) Stem Cells increase red blood cell production
B)
A)
D)
C)
Erythrocytes last for about ____ days, and as they mature, they make _____ and lose their nucleus and organelles
120
hemoglobin
results from the fragmentation of large cells
platelets (thrombocytes)
The formation of a blood clot requires ______, _______, and ___ clotting factors
platelets
calcium
13
- Blood vessel is punctured
- Platelets congregate and form a plug
- Platelets and damaged tissue cells release prothrombin activator, which initiates a cascade of enzymatic reaction
- Fibrin threads form and trap red blood cells
How a blood clot forms
Activator + Ca2+ prothrombin=
Thrombin + fibronectin + Ca2=
thrombin
fibrin threads
Genetic disorder
deficiency in a clotting factor
Hemophilia
When embolus (clot dislodges and travels in the blood) blocks a blood vessel
Thromboembolism
_____ inhibits platelet aggregation
Aspirin
Portal vein thrombosis is a cause of _______
Jaundice