Rapid Review - Equation Review (1) Flashcards
Sensitivity
Sensitivity = TP / (TP + FN)
Specificity
Specificity = TN / (TN + FP)
Positive predictive value
PPV = TP / (TP + FP)
Negative predictive value
NPV = TN / (FN + TN)
Odds ratio (for case-control studies)
Odds ratio = (a/c) / (b/d) = (ad) / (bc)
Relative risk
Relative risk = [ a / (a+b) ] / [c / (c+d) ]
Attributable risk
Attributable risk = [ a / (a+b) ] - [ c / (c+d) ]
Number needed to treat
1 / absolute risk reduction
Number needed to harm
1 / attributable risk
Hardy-Weinberg equilibrium
p^2 + 2pq + q^2 = 1
p + q = 1
Volume of distribution
Vd = (amount of drug in the body) / (plasma drug concentration)
Half-life
t1/2 = (0.693 × Vx) / CL
Drug clearance
CL = (rate of elimination of drug) / (plasma drug concentration) CL = Vd × Ke (elimination constant)
Loading dose
LD = (Cp × Vd) / F
Maintenance dose
MD = (Cp × CL × tau) / F