quiz 9 Flashcards
zymogens have more amino acids than the active enzyme
true
enzymes involved in blood clotting and protein digestion are synthesized as inactive enzymes
true
allosteric enzymes are usually the last enzyme in a metabolic series of enzymes
false
allosteric enzymes have active sites for regulator molecules but no active sites for substrates
false
allosteric enzymes can prevent build up of metabolic products
true
in some metabolic pathways, the product is the inhibitor to the first enzyme of the pathway
true
irreversible inhibitors are usually poisons
true
all enzymes can have allosteric inhibition
false
doubling the concentration of the enzyme will always double the rate of the reaction
false
excess substrate, not after saturation
doubling the concentration of the substrate will always double the rate of the reaction
false
very high and very low temperatures can cause permanent denature of an enzyme
false
penicillinase is the enzyme that inhibits the last step in bacterial cell wall synthesis
false
clavulinic acid is actually an irreversible inhibitor of penicillin
false
penicillinase
in large doses curare can be fatal, and in small doses it can act as a muscle relaxant
true
acetylcholinesterase is the enzyme that converts choline and acetic acid to acetylcholine
false
acetylcholinesterase is permanently inhibited by nerve gas
true
if acetylcholinesterase is inhibited it can cause over stimulation of the muscles, convulsions and death
true
acetylcholinesterase has an incredibly fast turnover rate
true
nerve gas in small quantities can be a muscle relaxant
false
butulism blocks the receptor site for acetylecholine on the muscle
false
after a heart attack, certain nezymes will be found in large quantities than normal in the blood
true
tissue damage can cause enzymes to leak into the blood
true
computerized assay procedures can measure very small quantities of enzymes
true
covalent modification (putting on a phosphate) is useful for regulating enzymes of competing processes
true
glycogenolysis is the process of converting glucose to glycogen
false
in an emergency excess glucose can be excreted by the kidneys
true
hypoglycemia can affect the brain due to low blood sugar levels
true
NOT an anticoagulant
Tylenol
vitamin D
catalytic-ally active apoenzyme coenzyme holoenzyme zymogen cofactor proenzyme
holoenzyme
which inhibition can be reversed by adding an excess of substrate
competitive
which usually forms covalent bonds with the enzyme
irreversible
inhibitor looks like the substrate
competitive
lead poisoning destroys salt bridges of many enzymes, but it can be removed with EDTA lead poisoning is what kind of inhibition
noncompetitive
inhibitor binds to enzyme at different site than substrate but it can be removed
noncompetitive
nerve gas is what type of inhibitor
irreversible
sulfa drugs resemble the substrate need by bacteria to make folic acid
competitive
what is the inactive enzyme that is the precursor to the pepiddase found in the stomach
pepsinogen
active peptidase found in the small intestines
trypsin
what is the inactive precursor of thrombin
prothrombin
what are necessary for the precursor prothrombin to be converted to thrombin
thrombinogen
thromboplastin
calcium ions
vitamin K
thrombin causes ____ to be converted to _____
fibrinogen
to be converted into
fibrin
after the clot is not needed, it is digested by what active enzyme
plasmin
what is the formation of a clot within a blood vessel called
thrombosis
what is it called if the clot breaks loose and moves elsewhere
embolism
what compound causes the conversion of fibrinogen to fibrin
thrombin
what is the actual blood clot
fibrin
what is blood called when fibrinogen is removed
plasma
what is an anticoagulant because it complexes with Ca2+ which is needed for blood clotting
oxalic acid
citric acid
what is the anticoagulant found in small quantities in the blood at all times
heparin
what is the sugar part of ATP and NAD and FAD
ribose
what is the amine base part of ATP and NAD and FAD
adenine
what an enzyme is called that has slight structural differences depending upon what type of tissues is in it
isoenzyme
what hormone is called the famine hormone
glucagon
what enzyme catalyzes the conversion of glycogen to glucose-1-phosphate
glycogen phosphorylase
