(Q4) Diseases of the Endocrine System (Ch.17) Flashcards
1
Q
Giantism/ Gigantism
A
- A form of giantism is caused by the over-secretion of somatotropin (growth hormone) from the anterior pituitary/adenohypophysis gland
- Oversecretion of growth hormone during childhood causes giantism
2
Q
Dwarfism
A
- A form of dwarfism is caused by the under-secretion/hyposecretion of somatotropin (growth hormone)
- Hyposecretion of growth hormone during childhood causes dwarfism
3
Q
Acromegaly
A
A form of giantism is caused by the over-secretion/hypersecretionof somatotropin (growth hormone) during adulthood after the bones have ossified
- can be caused by an adenoma on the anterior pituitary gland
4
Q
Simmond’s Disease
A
- Diminished anterior pituitary gland function caused by ischemic necrosis or a tumor
- Accompanied by many abnormal hormonal occurrences
- (Can cause extreme emaciation, premature aging, wrinkling of the facial skin, loss of pubic and axillary hair, dental caries and loss of libido etc)
5
Q
Diabetes Insipidus
A
- A rare disorder that causes the body to make too much urine.
- Caused by the failure of the posterior pituitary gland to secrete a proper amount of vasopressin (anti-diuretic hormone)
- (Not associated with diabetes mellitus)
6
Q
Vasopressin/Antidiuretic Hormone
A
- Hormone made in the hypothalamus that decreases water excretion by the kidneys by increasing water reabsorption in the collecting ducts
- Without vasopressin, excessive amounts of water are lost through the urinary system and can cause serious dehydration
7
Q
Hyperthyroidism
A
- Overproduction of the hormone thyroxine (from the thyroid gland)
- Cause increased metabolism, weightloss, weakness, nervousness, profuse sweating etc.
8
Q
Grave’s Disease/ Exoththalmia Goiter
A
- A severe form of hyperthyroidism
- Causes all the symptoms of hyperthyroidism along with bulging eyeballs due to edema of the tissues in the back of the eyesockets
9
Q
Hypothyroidism
A
- Failure of the thyroid gland to produce sufficient thyroxine
- Affects heart rate, body temperature, and all aspects of metabolism.
10
Q
Cretinism
A
- Hypothyroidism that is congenital or occurs early in life
- Causes abnormal mental and physical development
11
Q
Myxedema
A
- Hypothyroidism that occurs during adulthood
- Causes slow metabolism, mental dullness, sluggishness, puffy skin due to mucous-like edema
12
Q
Goiter
A
- Term that refers to an increase in the size of the thyroid gland
- Simple goiter: occurs when the thyroid gland enlarges to overcome deficiencies in the production of thyroid hormone
- 2 types of simple goiters: endemic, sporadic
13
Q
Disorders of the Thyroid Associated with Goiters
A
- Hypersecretion
- Tumors
- Inflammations
- Iodine Deficiencies
14
Q
Hyperparathyroidism
A
- Overproduction of the hormone parathormone (from the parathyroid)
- Causes increased calcium levels because parathormone causes calcium to be drawn out of bones and into the bloodstream
- Often occurs because of tumor formation
- Causes softening and deformation of bones, formation of kidney stones, hardening of the arteries, heartbeat irregularities
15
Q
Hypoparathyroidism
A
- Failure of the parathyroid gland to produce sufficient parathormone
- Causes nerve cell irritability and overactivity: leads to abnormal, sustained muscle contractions (tetany)