(Q4) Diseases of the Endocrine System (Ch.17) Flashcards

1
Q

Giantism/ Gigantism

A
  • A form of giantism is caused by the over-secretion of somatotropin (growth hormone) from the anterior pituitary/adenohypophysis gland
  • Oversecretion of growth hormone during childhood causes giantism
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2
Q

Dwarfism

A
  • A form of dwarfism is caused by the under-secretion/hyposecretion of somatotropin (growth hormone)
  • Hyposecretion of growth hormone during childhood causes dwarfism
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3
Q

Acromegaly

A

A form of giantism is caused by the over-secretion/hypersecretionof somatotropin (growth hormone) during adulthood after the bones have ossified
- can be caused by an adenoma on the anterior pituitary gland

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4
Q

Simmond’s Disease

A
  • Diminished anterior pituitary gland function caused by ischemic necrosis or a tumor
  • Accompanied by many abnormal hormonal occurrences
  • (Can cause extreme emaciation, premature aging, wrinkling of the facial skin, loss of pubic and axillary hair, dental caries and loss of libido etc)
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5
Q

Diabetes Insipidus

A
  • A rare disorder that causes the body to make too much urine.
  • Caused by the failure of the posterior pituitary gland to secrete a proper amount of vasopressin (anti-diuretic hormone)
  • (Not associated with diabetes mellitus)
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6
Q

Vasopressin/Antidiuretic Hormone

A
  • Hormone made in the hypothalamus that decreases water excretion by the kidneys by increasing water reabsorption in the collecting ducts
  • Without vasopressin, excessive amounts of water are lost through the urinary system and can cause serious dehydration
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7
Q

Hyperthyroidism

A
  • Overproduction of the hormone thyroxine (from the thyroid gland)
  • Cause increased metabolism, weightloss, weakness, nervousness, profuse sweating etc.
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8
Q

Grave’s Disease/ Exoththalmia Goiter

A
  • A severe form of hyperthyroidism
  • Causes all the symptoms of hyperthyroidism along with bulging eyeballs due to edema of the tissues in the back of the eyesockets
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9
Q

Hypothyroidism

A
  • Failure of the thyroid gland to produce sufficient thyroxine
  • Affects heart rate, body temperature, and all aspects of metabolism.
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10
Q

Cretinism

A
  • Hypothyroidism that is congenital or occurs early in life
  • Causes abnormal mental and physical development
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11
Q

Myxedema

A
  • Hypothyroidism that occurs during adulthood
  • Causes slow metabolism, mental dullness, sluggishness, puffy skin due to mucous-like edema
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12
Q

Goiter

A
  • Term that refers to an increase in the size of the thyroid gland
  • Simple goiter: occurs when the thyroid gland enlarges to overcome deficiencies in the production of thyroid hormone
  • 2 types of simple goiters: endemic, sporadic
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13
Q

Disorders of the Thyroid Associated with Goiters

A
  • Hypersecretion
  • Tumors
  • Inflammations
  • Iodine Deficiencies
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14
Q

Hyperparathyroidism

A
  • Overproduction of the hormone parathormone (from the parathyroid)
  • Causes increased calcium levels because parathormone causes calcium to be drawn out of bones and into the bloodstream
  • Often occurs because of tumor formation
  • Causes softening and deformation of bones, formation of kidney stones, hardening of the arteries, heartbeat irregularities
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15
Q

Hypoparathyroidism

A
  • Failure of the parathyroid gland to produce sufficient parathormone
  • Causes nerve cell irritability and overactivity: leads to abnormal, sustained muscle contractions (tetany)
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16
Q

Tetany

A

A condition marked by intermittent muscular spasms, caused by malfunction of the parathyroid glands and a consequent deficiency of calcium.

17
Q

Cushing’s Syndrome

A
  • A form of hyperadrenalism
  • Overproduction of the glucocorticoid hormones (cortisol is one)
  • Causes increased sugar, lipids, and fats in the blood, a fatty hump between the shoulders, a rounded face (moon face), pink or purple stretch marks, high blood pressure, weakness, fatigue
18
Q

Addison’s Disease/ Hypocortisolism

A
  • A form of hypoadrenalism
  • Failure of the adrenal glands to produce hormones (including cortisol)
  • Causes brown or bronze skin discoloration, low blood pressure, digestive disturbances, dehydration, weakness
  • Usually an autoimmune disorder
19
Q

Waterhouse-Frederichsen Syndrome

A
  • A fulminating blood infection caused by meningococcus that affects the adrenal glands
  • WFS causes the adrenal glands to fail to produce proper levels of corticosteroids due to bleeding within the adrenal cortex
  • Causes severe adrenal hemorrhages, rapid circulatory failure, skin hemorrhages, death
20
Q

Diabetes Mellitus/ Sugar Diabetes

A
  • A disease of inadequate control of blood glucose levels
  • Caused by the failure of the pancreas to produce and secrete proper amounts of insulin
  • Causes hyperglycemia, glycosuria, polyuria, thirstiness, hunger, blurry vision, tiredness, acidosis, atherosclerosis etc.
  • Two types: Type 1, Type 2
21
Q

Hyperglycemia

A
  • Excess sugar in the blood
  • Uncontrolled hyperglycemia can lead to acidosis
  • Can be a complication of diabetes mellitus
22
Q

Glycosuria

A
  • Sugar in the urine
  • Can be a complication of diabetes mellitus
23
Q

Polyuria

A
  • Passage of excess quantities of urine
  • Can be a complication of diabetes mellitus
24
Q

Acidosis

A
  • A serious diabetes complication where the body produces excess blood acids (ketones).
  • Occurs when there isn’t enough insulin in the body
  • (when the body is deprived of glucose, it metabolizes fats and proteins. The breakdown of fats and proteins causes a buildup of fatty acids in the blood which dramatically lowers blood pH to acidic)
25
Q

Atherosclerosis

A
  • Thickening or hardening of the arteries caused by a buildup of plaque in the inner lining of an artery.
  • Can be a complication of diabetes mellitus
  • Atherosclerosis can cause myocardial infarctions (heart attacks), gangrene, blindness
26
Q

Embalming Considerations for Diseases of the Endocrine System

A
  • Circulation problems
  • Careful control of injection pressure and rate of flow
  • May need to use multiple injection sites
  • Treatment of gangrene
  • Edema
  • Discolorations
  • Possible deformities
27
Q

Pancreatic Cancer

A
  • Called the silent disease because of few early cancer signs
28
Q

Endemic/Colloid Goiter

A

Goiters formed as a result of a lack of iodine in the diet

29
Q

Sporadic Goiter/ Non-Toxic Goiter

A

Goiters formed as a result of an unknown cause, but may result from the use of certain medications like lithium and aminoglutethimide