Psychopathology-Drug therapy The Biological Approach To Treating OCD Flashcards
What is the primary class of drugs used to control the symptoms of OCD?
The primary class of drugs used for OCD are antidepressants called SSRIs (Selective Serotonin Reuptake Inhibitors), such as Fluoxetine (Prozac).
What do SSRIs selectively influence in the brain?
SSRIs selectively influence serotonin in the brain.
How do SSRIs work in the synapse?
SSRIs inhibit (slow down) the reuptake process of serotonin in the synapse, keeping serotonin present in the synaptic cleft and continuing to stimulate the postsynaptic neuron.
How do SSRIs help in reducing anxiety related to OCD?
By keeping serotonin in the synapse longer, SSRIs help normalize the activity of the worry circuit, thereby reducing anxiety.
How long do SSRIs typically take to reduce symptoms of OCD?
SSRIs can take three to four months to reduce symptoms of OCD.
What options are available if SSRIs are not effective for some patients?
The dosage of SSRIs can be increased, or other treatment options like anti-anxiety drugs (e.g., benzodiazepines), tricyclics, or SNRIs may be attempted.
How do benzodiazepines work in treating OCD symptoms?
Benzodiazepines enhance a neurotransmitter called GABA, slowing the central nervous system and resulting in general relaxation.
What are the effects of tricyclics and SNRIs, and why might they be used?
Tricyclics and SNRIs increase serotonin and noradrenaline and may be effective when SSRIs fail, but they can have more intense side effects due to their non-selective action on multiple neurotransmitters.
