PSL301: Cardio 8 Flashcards

1
Q

Pc

A

capillary hydrostatic pressure

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2
Q

Pif

A

interstitial fluid pressure

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3
Q

(pi)c

A

plasma colloid osmotic pressure

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4
Q

(pi)if

A

Interstitial fluid colloid pressure

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5
Q

Define: Pc

A

move fluid out

due to fluid pressure in blood

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6
Q

Define: Pif

A

move fluid in
Opposes outward movement of Pc
due to fluid pressure in ISF

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7
Q

Define: (pi)c

A

Move fluid in

if proteins in blood > proteins in ISF

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8
Q

Define: (pi)if

A

Move fluid out

if proteins in ISF > proteins in blood

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9
Q

Formula: net fluid pressure (at capillaries)

A

Fluid out - fluid in

[Pc + (pi)if] - [Pif + (pi)c]

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10
Q

Value: Pif

why?

A
  • 3 mmHg

Lymphatic system remove fluid

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11
Q

Value: Pc

A

45 to 10 mmHg

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12
Q

Value: (pi)if

why?

A

8 mmHg

Lympathic system remove proteins

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13
Q

Value: (pi)c

A

28 mmHg

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14
Q

Value: plasma protein concentration

A

7.3 mg/dl

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15
Q

What makes up the plasma proteins?

A

75% albumin
25% globulin
Very little fibrinogen

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16
Q

Value: interstitial protein concentration

A

3 mg/dl

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17
Q

If net fluid pressure is positive…

A

More fluid going out of vessel

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18
Q

If net fluid pressure is negative…

A

More fluid going into vessel

19
Q

Due to the gradient from Pc, __L of net flow outward per day

A

3L

20
Q

Forces that push fluid out of vessels

A
  1. Hydrostatic pressure
  2. Pressure from LACK OF fluid in ISF
  3. Interstitial colloid osmotic pressure
21
Q

Forces that push fluid into vessels

A
  1. plasma colloid osmotic pressure
22
Q

Value: mean hydrostatic pressure

A

17.3 mmHg

23
Q

Value: filtration coefficient

A

10 mL/min/mmHg

24
Q

Formula: filtration rate

A

filtration coefficient * net filtration pressure

25
Q

Value: net filtration rate

A

3 mL/min

that much fluid is deposited in ISF every minute

26
Q

Functions of lympathic system

A
  1. Return fluid & proteins to circulatory system
  2. Pick up fat from intestines and deliver to circulatory system
  3. Help trap pathogens
27
Q

Lymphatic system help prevent…

A

edema

28
Q

Lymph is derived from…

A

ISF

29
Q

Where does the lymphatic system drain into?

A

subclavian veins

30
Q

What determines lymph flow?

A
  1. Valves
  2. External compression (skeletal pump)
  3. Smooth muscle in lymph vessel
  4. Pif
31
Q

What if flow in lymphatic system is blocked?

A

Edema

32
Q

3 factors that might cause edema

A
  1. Increase hydrostatic pressure
  2. Decrease in plasma protein
  3. Increase in interstitial proteins
33
Q

Where does edema happen?

A

any vascularized tissue

34
Q

One specific edema disease is…

A

Elephantiasis

35
Q

What causes elephantiasis?

A

small parasitic roundworms

36
Q

What is the vector for elephantiasis?

A

Mosquitos

37
Q

Define: elephantiasis

A

abnormal enlargement of any part of the body due to obstruction of the lymphatic channels in the area

38
Q

Fluid accumulation in the abdomen is called…

A

Ascites

39
Q

Ascites

A

Accumulation of fluid in the abdomen

40
Q

Another name for abdomin

A

peritoneal cavity

41
Q

Disease of ascites

A

Kwashiorkor: lack of protein in diet

Liver cirrhosis: cannot produce enough albumin

42
Q

What may cause liver cirrhosis?

A

Alcoholism
Hepatitis
Fatty liver disease
Acetaminophen

43
Q

CVD includes…

A
  1. CHD
  2. Cerebrovascular disease
  3. Peripheral arterial disease
  4. Rheumatic heart disease
  5. Congenital heart disease
  6. Deep vein thrombosis & pulmonary embolism
44
Q

Rheumatic heart disease is caused by…

A

Streptococcus pyogenes infection -> Rheumatic fever