PSL301: Cardio 8 Flashcards

1
Q

Pc

A

capillary hydrostatic pressure

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2
Q

Pif

A

interstitial fluid pressure

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3
Q

(pi)c

A

plasma colloid osmotic pressure

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4
Q

(pi)if

A

Interstitial fluid colloid pressure

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5
Q

Define: Pc

A

move fluid out

due to fluid pressure in blood

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6
Q

Define: Pif

A

move fluid in
Opposes outward movement of Pc
due to fluid pressure in ISF

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7
Q

Define: (pi)c

A

Move fluid in

if proteins in blood > proteins in ISF

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8
Q

Define: (pi)if

A

Move fluid out

if proteins in ISF > proteins in blood

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9
Q

Formula: net fluid pressure (at capillaries)

A

Fluid out - fluid in

[Pc + (pi)if] - [Pif + (pi)c]

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10
Q

Value: Pif

why?

A
  • 3 mmHg

Lymphatic system remove fluid

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11
Q

Value: Pc

A

45 to 10 mmHg

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12
Q

Value: (pi)if

why?

A

8 mmHg

Lympathic system remove proteins

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13
Q

Value: (pi)c

A

28 mmHg

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14
Q

Value: plasma protein concentration

A

7.3 mg/dl

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15
Q

What makes up the plasma proteins?

A

75% albumin
25% globulin
Very little fibrinogen

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16
Q

Value: interstitial protein concentration

A

3 mg/dl

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17
Q

If net fluid pressure is positive…

A

More fluid going out of vessel

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18
Q

If net fluid pressure is negative…

A

More fluid going into vessel

19
Q

Due to the gradient from Pc, __L of net flow outward per day

20
Q

Forces that push fluid out of vessels

A
  1. Hydrostatic pressure
  2. Pressure from LACK OF fluid in ISF
  3. Interstitial colloid osmotic pressure
21
Q

Forces that push fluid into vessels

A
  1. plasma colloid osmotic pressure
22
Q

Value: mean hydrostatic pressure

23
Q

Value: filtration coefficient

A

10 mL/min/mmHg

24
Q

Formula: filtration rate

A

filtration coefficient * net filtration pressure

25
Value: net filtration rate
3 mL/min | that much fluid is deposited in ISF every minute
26
Functions of lympathic system
1. Return fluid & proteins to circulatory system 2. Pick up fat from intestines and deliver to circulatory system 3. Help trap pathogens
27
Lymphatic system help prevent...
edema
28
Lymph is derived from...
ISF
29
Where does the lymphatic system drain into?
subclavian veins
30
What determines lymph flow?
1. Valves 2. External compression (skeletal pump) 3. Smooth muscle in lymph vessel 4. Pif
31
What if flow in lymphatic system is blocked?
Edema
32
3 factors that might cause edema
1. Increase hydrostatic pressure 2. Decrease in plasma protein 3. Increase in interstitial proteins
33
Where does edema happen?
any vascularized tissue
34
One specific edema disease is...
Elephantiasis
35
What causes elephantiasis?
small parasitic roundworms
36
What is the vector for elephantiasis?
Mosquitos
37
Define: elephantiasis
abnormal enlargement of any part of the body due to obstruction of the lymphatic channels in the area
38
Fluid accumulation in the abdomen is called...
Ascites
39
Ascites
Accumulation of fluid in the abdomen
40
Another name for abdomin
peritoneal cavity
41
Disease of ascites
Kwashiorkor: lack of protein in diet | Liver cirrhosis: cannot produce enough albumin
42
What may cause liver cirrhosis?
Alcoholism Hepatitis Fatty liver disease Acetaminophen
43
CVD includes...
1. CHD 2. Cerebrovascular disease 3. Peripheral arterial disease 4. Rheumatic heart disease 5. Congenital heart disease 6. Deep vein thrombosis & pulmonary embolism
44
Rheumatic heart disease is caused by...
Streptococcus pyogenes infection -> Rheumatic fever