Proto-oncogenes Flashcards

1
Q

BRAF

A

Serina/treonina kinasa
Melanoma y tiroides medular

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2
Q

Proto-oncogenes de receptor tirosin kinasa

A
  • ERBB2 (HER2): Mama y gastro
  • ALK: Pulmón
  • RET: MEN 2A (medular, feocromocitoma e hiperplasia o adenomas paratiroideos) Y 2B (medular, feocromocitoma, ganglioneuromas)
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3
Q

cKIT

A

Receptor citocina
GIST

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4
Q

Factores de transcripción

A

Lmyc: pulmón
Nmyc: neuroblastoma
Cmyc: BURKIT

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5
Q

KRAS

A

GTPasa
Colorrecto, pulmón, páncreas

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6
Q

ERBB1

A

EGFR
PULMÓN NSCLC

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