Genes supresores de tumores Flashcards

1
Q

TP 53

A

P53
Apoptosis (BAX): G1: INH P DE RB (S)

LI FRAUMENI

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2
Q

APC

A

Inhibe la prod de B-catenina
Polipo adenomatoso familiar y colorrecto

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3
Q

CDKN2A

A

p16 que arresta ciclo cel en G1
Melanoma, páncreas y pulmón.

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4
Q

PTEN

A

Mama, endometrio, próstata
COWDEN

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5
Q

BRCA 1 y 2

A

Mama, ovario, páncreas

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