Prostate Path Flashcards

1
Q

What are the three zones of the prostate

A

Peripheral, central, transitional

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2
Q

What is the largest zone of the prostate and most associated with prostate cancer?

A

Peripheral zone

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3
Q

BPH occurs in which zone?

A

Transitional

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4
Q

Only the ___ cells become neoplastic

A

secretory

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5
Q

BPH is the most common non-cancerous cause of __

A

PSA

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6
Q

___ men have a higher rate and more aggressive prostate cancer

A

Black

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7
Q

Invasive cancer loses the __ layer of cells

A

basal

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8
Q

A tumor volume of less than __ CC indicates a very low risk of progressoin

A

0.5

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9
Q
Staging
T1a
T1b
T1c
T2a
T2b
T2c
T3a
T3b
T4
A
5%
Only seen in needle biopsy
50% of one lobe
Both Lobes
Spread to extraprostatic tissue
spread to seminal vesicle
Metastasis
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10
Q
Gleason Grading 
1 & 2
3
4 
5
A

well formed glands
irregular gland infiltration
Cribriform plates
Cell sheets without any gland formation

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