Gyn Path III Flashcards
Three most common cell types for surface epithelial ovarian tumors
Serous, Mucinous, Endometrioid
Benign tumors are lined by a __ ____ of cells
single layer
Ovarian masses that are both __ and __ are malignant
solid; cystic
Ovarian cancers like to spread to the ____ and the ___
peritoneum and omentum
Ovarian __ carcinoma is the most common
serous
Low grade ovarian serous carcinomas have __ or ___ mutations
BRAF; KRAS
High grade ovarian serous carcinomas have ___ mutations
p53
Borderline ovarian tumors lack ___ ___
stromal invasion
Borderline tumors which spread outside the ovary are called
implants
Surface epithelial tumors occur in ___ patients (age) while germ cell tumors occur in __ patients (age)
older; younger
Teratomas most commonly have ___ epitheliums
squamous
The most common malignant tumor in women in their 2nd and third decade is a ____, which has an ___ prognosis
dysgerminoma; excellent
Sex cord stromal tumors arise from __ and __ cells
granulosa; theca
Granulosa cell tumors can produce ____ and cause ___ proliferation
estrogen; endometrial
Granulosa cell tumors look ____ histologically
all the same