Genetic Breast Cancer Flashcards
The single most dietary factor for breast cancer is
alcohol
The mutation is the __ gene trumps any minor risk factors for the individual but minor risk factors like ___ are more important at the population level
BRCA; obesity
Breast cancers have less __ components and are more sporadic
hereditary
BRCA genes code for ____ ___ and need a loss of __ to be deletrious
tumor suppressors; heterozygosity
BRCA2 is implicated in causing other cancers with the exception of ___ cancer, which BRCA1 is more associated with
ovarian
__ jews should be tested for breast cancer gene
Ashkenazi
The ___ procedure reduces the risk of both breast and ovarian cancer
salpingo-oophorectomy
BRCA genes repair
DS DNA breaks
PARP inhibitors cause __ in cells
DS DNA breaks
Patients who have relatives with breast cancer and are ___ __ should undergo the same breast cancer screenings as the population
true negatives
CDH1 mutations are associated with __ cancer
gastric