PCOS Flashcards
Two criteria for PCOS
irregular menses and cystic ovaries and hyperandrogenemia (any two of these three)
Irregular periods are __ days apart
45
Clinical signs of hyperandrogenemia include hair growth where?
In the midline of the body
The primary marker of hyperandrogenemia is high
free testosterone
PCOS women also have high
anti-mullerian hormone
Obesity is __ of PCOS
modifier
PCOS patients have more __ fat and deposit fat __
abdominal; centrally
PCOS has frequent, rapid release of
GnRH
You have an ___ LH to FSH ratio
high
Increased LH causes __ cells to release more testosterone
thecal
Granulosa cells have an increased response to __ in PCOS
FSH
PCOS women have __ resistance which increases testosterone release from thecal cells due to higher levels of __
insulin
This presents with velvety, hyperpigmented skin, and is seen in insulin resistance. Associated with PCOS
Acanthosis Nigricans
What is the insulin receptor defect in PCOS
none haha
PCOS patients who want to get pregnant only need help to
ovulate