Prochlorperazine Flashcards

1
Q

Presentation of Prochlorperazine

A

12.5mg in 1ml amp

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2
Q

Pharmacology of Prochlorperazine

A

Anti-emetic

Action:
- Acts on several central neuro-transmitter systems

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3
Q

Metabolism of Prochlorperazine

A

Metabolised by the liver and excreted by the kidneys

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4
Q

Prochlorperazine Indications

A

Treatment or prophylaxis of nausea/vomiting for:

  • Motion sickness
  • Vertigo
  • Planned areomedical evacuation
  • Headache irrespective of nausea/vomiting
  • Known allergy or contraindication to Metoclopramide administration
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5
Q

Prochlorperazine Contraindications

A
  • Previous hypersensitivity
  • CNS depression
  • Circulatory collapse
  • Children
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6
Q

Prochlorperazine Precautions

A
  • Hypotension
  • Epilepsy
  • Pts effected by alcohol or on anti-depressants
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7
Q

Route of Administration of Prochlorperazine

A

IM

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8
Q

Side Effects of Prochloperazine

A
  • Blurred vision
  • Sinus tachycardia
  • Skin rash
  • Hypotension
  • Extrapyramidal reactions
  • Drowsiness
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9
Q

Effects of Prochlorperazine

A

IM
Onset: 20min
Peak: 40min
Duration: 6hrs

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