Metoclopramide Flashcards
1
Q
Presentation of Metoclopramide
A
10mg in 2ml ampule
2
Q
Pharmacology of Metoclopramide
A
- Antiemetic which accelerates gastric emptying and peristalsis
- Mild SHT3-receptor antagonist
3
Q
Metabolism of Metoclopramide
A
By the liver and excreted by the kidneys
4
Q
Metoclopramide Indications
A
Nausea/Vomiting associated with:
- Chest pain/discomfort of a cardiac nature
- Opiod administration for pain
- Previously diagnosed migrane
- Severe gastroenteritis
- Eye trauma
- Cytotoxic or radiotherpy
- Treatment or prophylaxis in awake spinal immobilised pts
5
Q
Metoclopramide Contraindications
A
- Suspected bowel obstruction or perforation
- Children
- GI haemorrhage
6
Q
Metoclopramide Precautions
A
- Undiagnosed abdo pain
- Adolescents (<20yrs)
- Administer slowly over one minute to minimise risk of extrapyramidial reactions
7
Q
Route of Administration of Metoclopramide
A
IV
IM
8
Q
Side Effects of Metoclopramide
A
- Muscle tremor
- Extrapyramidal reactions
- Drowsiness
- Dry mouth
- Lethergy
9
Q
Effects of Metoclopramide
A
IV
Onset: 1-3min
Duration: 10-30min
IM
Onset: 10-15min
Duration: 1-2hr
