Misoprostol Flashcards
1
Q
Presentation of Misoprostol
A
200mcg tablet
2
Q
Pharmacology of Misoprostol
A
Synthetic prostaglandin
3
Q
Metabolism of Misoprostol
A
- Converted to active metabolite Misoprostol Acid in the blood
- Metabolised in the tissues and excreted by the kidneys
4
Q
Misoprostol Indications
A
Primary Post Partum Haemorrhage
5
Q
Misoprostol Contraindications
A
Allergy to prostaglandins
Ensure multiple prenancy excluded before drug administration
6
Q
Misoprostol Precautions
A
History of asthma
7
Q
Route of Administration of Misoprostol
A
Oral
8
Q
Side Effects of Misoprostol
A
- Abdominal pain and Diarrhoea
- Shivering
- Hyper-pyrexia
9
Q
Effects of Misoprostol
A
Oral
Onset: 8-10min
Duration: 2-3hrs
10
Q
Misoprostol Special Notes
A
Side effects more likely with >600mcg oral dose
